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Principles for optimization and validation of mRNA lipid nanoparticle vaccines against COVID-19 using 3D bioprinting
BioNTech/Pfizer’s Comirnaty and Moderna’s SpikeVax vaccines consist in mRNA encapsulated in lipid nanoparticles (LNPs). The modularity of the delivery platform and the manufacturing possibilities provided by microfluidics let them look like an instant success, but they are the product of decades of...
Autores principales: | Papi, Massimiliano, Pozzi, Daniela, Palmieri, Valentina, Caracciolo, Giulio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776405/ https://www.ncbi.nlm.nih.gov/pubmed/35079274 http://dx.doi.org/10.1016/j.nantod.2022.101403 |
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