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One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19

BACKGROUND: There is a limited data about the one-year outcomes of patients diagnosed with acute coronary syndrome (ACS) and coronavirus disease 2019 (COVID-19). OBJECTIVES: To assess one-year mortality of invasively managed patients with ACS and COVID-19 compared to ACS patients without COVID-19. M...

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Autores principales: Çınar, Tufan, Şaylık, Faysal, Akbulut, Tayyar, Asal, Suha, Selçuk, Murat, Çiçek, Vedat, Kılıç, Şahhan, Orhan, Ahmet Lütfullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776464/
https://www.ncbi.nlm.nih.gov/pubmed/35092905
http://dx.doi.org/10.1016/j.hrtlng.2022.01.012
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author Çınar, Tufan
Şaylık, Faysal
Akbulut, Tayyar
Asal, Suha
Selçuk, Murat
Çiçek, Vedat
Kılıç, Şahhan
Orhan, Ahmet Lütfullah
author_facet Çınar, Tufan
Şaylık, Faysal
Akbulut, Tayyar
Asal, Suha
Selçuk, Murat
Çiçek, Vedat
Kılıç, Şahhan
Orhan, Ahmet Lütfullah
author_sort Çınar, Tufan
collection PubMed
description BACKGROUND: There is a limited data about the one-year outcomes of patients diagnosed with acute coronary syndrome (ACS) and coronavirus disease 2019 (COVID-19). OBJECTIVES: To assess one-year mortality of invasively managed patients with ACS and COVID-19 compared to ACS patients without COVID-19. METHODS: In our investigation, we defined the study time period as April 30 through September 1, 2020. The control groups consisted of ACS patients without COVID-19 at the same time period and ACS patients prior to the pandemic, within the same months as those of the study. COVID-19 infection was confirmed in all participants utilizing real-time polymerase chain reaction testing. RESULTS: This investigation examined 721 ACS participants in total. Among the participants, 119 patients were diagnosed with ACS and COVID-19, while 149 were diagnosed with ACS and without COVID-19. The other 453 ACS participants were diagnosed before the outbreak of the pandemic, within the same months as those of the study. One-year mortality rates were higher in the ACS participants with COVID-19 than in the ACS participants without COVID-19 and the pre-COVID-19 ACS participants (21.3% vs. 6.5% vs. 6.9%, respectively). An ACS along with COVID-19 was the only independent predictor of one-year mortality (HR=2.902, 95%CI=1.211–6.824, P = 0.018). According to the Kaplan-Meier survival curves, patients with ACS and COVID-19 had a lower chance of survival in the short-term and one-year periods. CONCLUSION: This is believed to be the first study to report that ACS patients with COVID-19 had higher one-year risk of mortality compared to ACS patients without COVID-19.
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spelling pubmed-87764642022-01-21 One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19 Çınar, Tufan Şaylık, Faysal Akbulut, Tayyar Asal, Suha Selçuk, Murat Çiçek, Vedat Kılıç, Şahhan Orhan, Ahmet Lütfullah Heart Lung Article BACKGROUND: There is a limited data about the one-year outcomes of patients diagnosed with acute coronary syndrome (ACS) and coronavirus disease 2019 (COVID-19). OBJECTIVES: To assess one-year mortality of invasively managed patients with ACS and COVID-19 compared to ACS patients without COVID-19. METHODS: In our investigation, we defined the study time period as April 30 through September 1, 2020. The control groups consisted of ACS patients without COVID-19 at the same time period and ACS patients prior to the pandemic, within the same months as those of the study. COVID-19 infection was confirmed in all participants utilizing real-time polymerase chain reaction testing. RESULTS: This investigation examined 721 ACS participants in total. Among the participants, 119 patients were diagnosed with ACS and COVID-19, while 149 were diagnosed with ACS and without COVID-19. The other 453 ACS participants were diagnosed before the outbreak of the pandemic, within the same months as those of the study. One-year mortality rates were higher in the ACS participants with COVID-19 than in the ACS participants without COVID-19 and the pre-COVID-19 ACS participants (21.3% vs. 6.5% vs. 6.9%, respectively). An ACS along with COVID-19 was the only independent predictor of one-year mortality (HR=2.902, 95%CI=1.211–6.824, P = 0.018). According to the Kaplan-Meier survival curves, patients with ACS and COVID-19 had a lower chance of survival in the short-term and one-year periods. CONCLUSION: This is believed to be the first study to report that ACS patients with COVID-19 had higher one-year risk of mortality compared to ACS patients without COVID-19. Elsevier Inc. 2022 2022-01-21 /pmc/articles/PMC8776464/ /pubmed/35092905 http://dx.doi.org/10.1016/j.hrtlng.2022.01.012 Text en © 2022 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Çınar, Tufan
Şaylık, Faysal
Akbulut, Tayyar
Asal, Suha
Selçuk, Murat
Çiçek, Vedat
Kılıç, Şahhan
Orhan, Ahmet Lütfullah
One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19
title One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19
title_full One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19
title_fullStr One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19
title_full_unstemmed One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19
title_short One-year outcomes of invasively managed acute coronary syndrome patients with COVID-19
title_sort one-year outcomes of invasively managed acute coronary syndrome patients with covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776464/
https://www.ncbi.nlm.nih.gov/pubmed/35092905
http://dx.doi.org/10.1016/j.hrtlng.2022.01.012
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