Supramolecular Arrangement of Protein in Nanoparticle Structures Predicts Nanoparticle Tropism for Neutrophils in Acute Lung Inflammation

This study shows that supramolecular arrangement of proteins in nanoparticle structure predicts nanoparticle accumulation in neutrophils in acute lung inflammation (ALI). We observed homing to inflamed lungs for a variety of nanoparticles with agglutinated protein (NAPs), defined by arrangement of p...

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Detalles Bibliográficos
Autores principales: Myerson, Jacob W., Patel, Priyal N., Rubey, Kathryn M., Zamora, Marco E., Zaleski, Michael H., Habibi, Nahal, Walsh, Landis R., Lee, Yi-Wei, Luther, David C., Ferguson, Laura T., Marcos-Contreras, Oscar A., Glassman, Patrick M., Mazaleuskaya, Liudmila L., Johnston, Ian, Hood, Elizabeth D., Shuvaeva, Tea, Wu, Jichuan, Zhang, Hong-Ying, Gregory, Jason V., Kiseleva, Raisa Y., Nong, Jia, Grosser, Tilo, Greineder, Colin F., Mitragotri, Samir, Worthen, George S., Rotello, Vincent M., Lahann, Joerg, Muzykantov, Vladimir R., Brenner, Jacob S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776575/
https://www.ncbi.nlm.nih.gov/pubmed/34795440
http://dx.doi.org/10.1038/s41565-021-00997-y

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