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Ovarian Biomechanics: From Health to Disease

Biomechanics is a physical phenomenon which mainly related with deformation and movement of life forms. As a mechanical signal, it participates in the growth and development of many tissues and organs, including ovary. Mechanical signals not only participate in multiple processes in the ovary but al...

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Detalles Bibliográficos
Autores principales: Sun, Chenchen, Yang, Xiaoxu, Wang, Tianxiao, Cheng, Min, Han, Yangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776636/
https://www.ncbi.nlm.nih.gov/pubmed/35070963
http://dx.doi.org/10.3389/fonc.2021.744257
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author Sun, Chenchen
Yang, Xiaoxu
Wang, Tianxiao
Cheng, Min
Han, Yangyang
author_facet Sun, Chenchen
Yang, Xiaoxu
Wang, Tianxiao
Cheng, Min
Han, Yangyang
author_sort Sun, Chenchen
collection PubMed
description Biomechanics is a physical phenomenon which mainly related with deformation and movement of life forms. As a mechanical signal, it participates in the growth and development of many tissues and organs, including ovary. Mechanical signals not only participate in multiple processes in the ovary but also play a critical role in ovarian growth and normal physiological functions. Additionally, the involvement of mechanical signals has been found in ovarian cancer and other ovarian diseases, prompting us to focus on the roles of mechanical signals in the process of ovarian health to disease. This review mainly discusses the effects and signal transduction of biomechanics (including elastic force, shear force, compressive stress and tensile stress) in ovarian development as a regulatory signal, as well as in the pathological process of normal ovarian diseases and cancer. This review also aims to provide new research ideas for the further research and treatment of ovarian-related diseases.
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spelling pubmed-87766362022-01-22 Ovarian Biomechanics: From Health to Disease Sun, Chenchen Yang, Xiaoxu Wang, Tianxiao Cheng, Min Han, Yangyang Front Oncol Oncology Biomechanics is a physical phenomenon which mainly related with deformation and movement of life forms. As a mechanical signal, it participates in the growth and development of many tissues and organs, including ovary. Mechanical signals not only participate in multiple processes in the ovary but also play a critical role in ovarian growth and normal physiological functions. Additionally, the involvement of mechanical signals has been found in ovarian cancer and other ovarian diseases, prompting us to focus on the roles of mechanical signals in the process of ovarian health to disease. This review mainly discusses the effects and signal transduction of biomechanics (including elastic force, shear force, compressive stress and tensile stress) in ovarian development as a regulatory signal, as well as in the pathological process of normal ovarian diseases and cancer. This review also aims to provide new research ideas for the further research and treatment of ovarian-related diseases. Frontiers Media S.A. 2022-01-07 /pmc/articles/PMC8776636/ /pubmed/35070963 http://dx.doi.org/10.3389/fonc.2021.744257 Text en Copyright © 2022 Sun, Yang, Wang, Cheng and Han https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Sun, Chenchen
Yang, Xiaoxu
Wang, Tianxiao
Cheng, Min
Han, Yangyang
Ovarian Biomechanics: From Health to Disease
title Ovarian Biomechanics: From Health to Disease
title_full Ovarian Biomechanics: From Health to Disease
title_fullStr Ovarian Biomechanics: From Health to Disease
title_full_unstemmed Ovarian Biomechanics: From Health to Disease
title_short Ovarian Biomechanics: From Health to Disease
title_sort ovarian biomechanics: from health to disease
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776636/
https://www.ncbi.nlm.nih.gov/pubmed/35070963
http://dx.doi.org/10.3389/fonc.2021.744257
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