Neural Substrates of the Drift-Diffusion Model in Brain Disorders

Many studies on the drift-diffusion model (DDM) explain decision-making based on a unified analysis of both accuracy and response times. This review provides an in-depth account of the recent advances in DDM research which ground different DDM parameters on several brain areas, including the cortex...

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Autores principales: Gupta, Ankur, Bansal, Rohini, Alashwal, Hany, Kacar, Anil Safak, Balci, Fuat, Moustafa, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776710/
https://www.ncbi.nlm.nih.gov/pubmed/35069160
http://dx.doi.org/10.3389/fncom.2021.678232
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author Gupta, Ankur
Bansal, Rohini
Alashwal, Hany
Kacar, Anil Safak
Balci, Fuat
Moustafa, Ahmed A.
author_facet Gupta, Ankur
Bansal, Rohini
Alashwal, Hany
Kacar, Anil Safak
Balci, Fuat
Moustafa, Ahmed A.
author_sort Gupta, Ankur
collection PubMed
description Many studies on the drift-diffusion model (DDM) explain decision-making based on a unified analysis of both accuracy and response times. This review provides an in-depth account of the recent advances in DDM research which ground different DDM parameters on several brain areas, including the cortex and basal ganglia. Furthermore, we discuss the changes in DDM parameters due to structural and functional impairments in several clinical disorders, including Parkinson's disease, Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorders, Obsessive-Compulsive Disorder (OCD), and schizophrenia. This review thus uses DDM to provide a theoretical understanding of different brain disorders.
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spelling pubmed-87767102022-01-22 Neural Substrates of the Drift-Diffusion Model in Brain Disorders Gupta, Ankur Bansal, Rohini Alashwal, Hany Kacar, Anil Safak Balci, Fuat Moustafa, Ahmed A. Front Comput Neurosci Neuroscience Many studies on the drift-diffusion model (DDM) explain decision-making based on a unified analysis of both accuracy and response times. This review provides an in-depth account of the recent advances in DDM research which ground different DDM parameters on several brain areas, including the cortex and basal ganglia. Furthermore, we discuss the changes in DDM parameters due to structural and functional impairments in several clinical disorders, including Parkinson's disease, Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorders, Obsessive-Compulsive Disorder (OCD), and schizophrenia. This review thus uses DDM to provide a theoretical understanding of different brain disorders. Frontiers Media S.A. 2022-01-07 /pmc/articles/PMC8776710/ /pubmed/35069160 http://dx.doi.org/10.3389/fncom.2021.678232 Text en Copyright © 2022 Gupta, Bansal, Alashwal, Kacar, Balci and Moustafa. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Gupta, Ankur
Bansal, Rohini
Alashwal, Hany
Kacar, Anil Safak
Balci, Fuat
Moustafa, Ahmed A.
Neural Substrates of the Drift-Diffusion Model in Brain Disorders
title Neural Substrates of the Drift-Diffusion Model in Brain Disorders
title_full Neural Substrates of the Drift-Diffusion Model in Brain Disorders
title_fullStr Neural Substrates of the Drift-Diffusion Model in Brain Disorders
title_full_unstemmed Neural Substrates of the Drift-Diffusion Model in Brain Disorders
title_short Neural Substrates of the Drift-Diffusion Model in Brain Disorders
title_sort neural substrates of the drift-diffusion model in brain disorders
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776710/
https://www.ncbi.nlm.nih.gov/pubmed/35069160
http://dx.doi.org/10.3389/fncom.2021.678232
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