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An EPA database on the effects of engineered nanomaterials-NaKnowBase

The US EPA Office of Research and Development (ORD) has conducted a research program assessing potential risks of emerging materials and technologies, including engineered nanomaterials (ENM). As a component of that program, a nanomaterial knowledge base, termed “NaKnowBase”, was developed containin...

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Autores principales: Boyes, William K., Beach, Bradley, Chan, Gayle, Thornton, B. Lila M., Harten, Paul, Mortensen, Holly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776817/
https://www.ncbi.nlm.nih.gov/pubmed/35058454
http://dx.doi.org/10.1038/s41597-021-01098-0
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author Boyes, William K.
Beach, Bradley
Chan, Gayle
Thornton, B. Lila M.
Harten, Paul
Mortensen, Holly M.
author_facet Boyes, William K.
Beach, Bradley
Chan, Gayle
Thornton, B. Lila M.
Harten, Paul
Mortensen, Holly M.
author_sort Boyes, William K.
collection PubMed
description The US EPA Office of Research and Development (ORD) has conducted a research program assessing potential risks of emerging materials and technologies, including engineered nanomaterials (ENM). As a component of that program, a nanomaterial knowledge base, termed “NaKnowBase”, was developed containing the results of published ORD research relevant to the potential environmental and biological actions of ENM. The experimental data address issues such as ENM release into the environment; fate, transport and transformations in environmental media; exposure to ecological species or humans; and the potential for effects on those species. The database captures information on the physicochemical properties of ENM tested, assays performed and their parameters, and the results obtained. NaKnowBase (NKB) is a relational SQL database, and may be queried either with SQL code or through a user-friendly web interface. Filtered results may be output in spreadsheet format for subsequent user-defined analyses. Potential uses of the data might include input to quantitative structure-activity relationships (QSAR), meta-analyses, or other investigative approaches.
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spelling pubmed-87768172022-02-04 An EPA database on the effects of engineered nanomaterials-NaKnowBase Boyes, William K. Beach, Bradley Chan, Gayle Thornton, B. Lila M. Harten, Paul Mortensen, Holly M. Sci Data Data Descriptor The US EPA Office of Research and Development (ORD) has conducted a research program assessing potential risks of emerging materials and technologies, including engineered nanomaterials (ENM). As a component of that program, a nanomaterial knowledge base, termed “NaKnowBase”, was developed containing the results of published ORD research relevant to the potential environmental and biological actions of ENM. The experimental data address issues such as ENM release into the environment; fate, transport and transformations in environmental media; exposure to ecological species or humans; and the potential for effects on those species. The database captures information on the physicochemical properties of ENM tested, assays performed and their parameters, and the results obtained. NaKnowBase (NKB) is a relational SQL database, and may be queried either with SQL code or through a user-friendly web interface. Filtered results may be output in spreadsheet format for subsequent user-defined analyses. Potential uses of the data might include input to quantitative structure-activity relationships (QSAR), meta-analyses, or other investigative approaches. Nature Publishing Group UK 2022-01-20 /pmc/articles/PMC8776817/ /pubmed/35058454 http://dx.doi.org/10.1038/s41597-021-01098-0 Text en © This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) applies to the metadata files associated with this article.
spellingShingle Data Descriptor
Boyes, William K.
Beach, Bradley
Chan, Gayle
Thornton, B. Lila M.
Harten, Paul
Mortensen, Holly M.
An EPA database on the effects of engineered nanomaterials-NaKnowBase
title An EPA database on the effects of engineered nanomaterials-NaKnowBase
title_full An EPA database on the effects of engineered nanomaterials-NaKnowBase
title_fullStr An EPA database on the effects of engineered nanomaterials-NaKnowBase
title_full_unstemmed An EPA database on the effects of engineered nanomaterials-NaKnowBase
title_short An EPA database on the effects of engineered nanomaterials-NaKnowBase
title_sort epa database on the effects of engineered nanomaterials-naknowbase
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776817/
https://www.ncbi.nlm.nih.gov/pubmed/35058454
http://dx.doi.org/10.1038/s41597-021-01098-0
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