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TGF-β1 Drives Inflammatory Th Cell But Not Treg Cell Compartment Upon Allergen Exposure
TGF-β1 is known to have a pro-inflammatory impact by inducing Th9 and Th17 cells, while it also induces anti-inflammatory Treg cells (Tregs). In the context of allergic airway inflammation (AAI) its dual role can be of critical importance in influencing the outcome of the disease. Here we demonstrat...
Autores principales: | Musiol, Stephanie, Alessandrini, Francesca, Jakwerth, Constanze A., Chaker, Adam M., Schneider, Evelyn, Guerth, Ferdinand, Schnautz, Benjamin, Grosch, Johanna, Ghiordanescu, Ileana, Ullmann, Julia T., Kau, Josephine, Plaschke, Mirjam, Haak, Stefan, Buch, Thorsten, Schmidt-Weber, Carsten B., Zissler, Ulrich M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777012/ https://www.ncbi.nlm.nih.gov/pubmed/35069535 http://dx.doi.org/10.3389/fimmu.2021.763243 |
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