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Vaccine Protection of Mice With Primary Immunodeficiencies Against Disseminated Coccidioidomycosis

Disseminated coccidioidomycosis (DCM), often a severe and refractory disease leading to poor outcomes, is a risk for people with certain primary immunodeficiencies (PID). Several DCM-associated PID (STAT4, STAT3, IFNγ, and Dectin-1) are modeled in mice. To determine if vaccination could provide thes...

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Detalles Bibliográficos
Autores principales: Powell, Daniel A., Hsu, Amy P., Butkiewicz, Christine D., Trinh, Hien T., Frelinger, Jeffrey A., Holland, Steven M., Galgiani, John N., Shubitz, Lisa F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777018/
https://www.ncbi.nlm.nih.gov/pubmed/35071044
http://dx.doi.org/10.3389/fcimb.2021.790488