T-follicular helper cell expansion and chronic T-cell activation are characteristic immune anomalies in Evans syndrome

Pediatric Evans syndrome (pES) is increasingly identified as the presenting manifestation of several inborn errors of immunity. Despite an improved understanding of genetic defects in pES, the underlying immunobiology of pES is poorly defined, and characteristic diagnostic immune parameters are lack...

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Detalles Bibliográficos
Autores principales: Kumar, Deepak, Prince, Chengyu, Bennett, Carolyn M., Briones, Michael, Lucas, Laura, Russell, Athena, Patel, Kiran, Chonat, Satheesh, Graciaa, Sara, Edington, Holly, White, Michael H., Kobrynski, Lisa, Abdalgani, Manar, Parikh, Suhag, Chandra, Sharat, Bleesing, Jack, Marsh, Rebecca, Park, Sunita, Waller, Edmund K., Prahalad, Sampath, Chandrakasan, Shanmuganathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Immunobiology and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777200/
https://www.ncbi.nlm.nih.gov/pubmed/34424963
http://dx.doi.org/10.1182/blood.2021012924

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