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Altered expression of miR-29a-3p and miR-34a-5p by specific inhibition of GSK3β in the MPP(+) treated SH-SY5Y Parkinson's model

In the current study, the effects of 7-BIO as a specific GSK3β inhibitor was examined on cell survival and expression of miR-29a-3p and miR-34a-5p in neurotoxin MPP(+) treated SH-SY5Y cells. Our findings revealed that while co-treatment of the cells with 7-BIO and MPP(+) did not alter the toxicity i...

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Detalles Bibliográficos
Autores principales: Ahmadzadeh-Darinsoo, Morteza, Ahmadzadeh-Darinsoo, Mojtaba, Abbasi, Shahsanam, Arefian, Ehsan, Bernard, Claude, Tafreshi, Azita Parvaneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777260/
https://www.ncbi.nlm.nih.gov/pubmed/35087989
http://dx.doi.org/10.1016/j.ncrna.2021.12.004