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PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway
Dendritic cells (DCs) are recognized as a key orchestrator of immune response and homeostasis, deregulation of which may lead to autoimmunity such as experimental autoimmune encephalomyelitis (EAE). Herein we show that the phosphatase PP2Cδ played a pivotal role in regulating DC activation and funct...
Autores principales: | Lv, Nianyin, Jin, Sufeng, Liang, Zihao, Wu, Xiaohui, Kang, Yanhua, Su, Lan, Dong, Yeping, Wang, Bingwei, Ma, Tonghui, Shi, Liyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777276/ https://www.ncbi.nlm.nih.gov/pubmed/35069527 http://dx.doi.org/10.3389/fimmu.2021.751409 |
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