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Intratumoral gene expression of dihydrofolate reductase and folylpoly-c-glutamate synthetase affects the sensitivity to 5-fluorouracil in non-small cell lung cancer

BACKGROUND: Various factors related to the sensitivity of non-small cell lung carcinoma (NSCLC) to 5-fluorouracil (5-FU) have been reported, and some of them have been clinically applied. In this single-institutional prospective analysis, the mRNA expression level of five folic acid-associated enzym...

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Detalles Bibliográficos
Autores principales:	Sakon, Kayo, Sasaki, Masato, Tanaka, Kaede, Mizunaga, Tae, Yano, Keita, Kawamura, Yuuko, Okada, Akitoshi, Ikeda, Takeshi, Tanabe, Sawaka, Takamori, Atsushi, Yamada, Narihisa, Morioka, Kouichi, Koshiji, Takaaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777502/ https://www.ncbi.nlm.nih.gov/pubmed/35201464 http://dx.doi.org/10.1007/s12672-021-00413-w

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