Cargando…

Emerging roles of the HECT-type E3 ubiquitin ligases in hematological malignancies

Ubiquitination-mediated proteolysis or regulation of proteins, ultimately executed by E3 ubiquitin ligases, control a wide array of cellular processes, including transcription, cell cycle, autophagy and apoptotic cell death. HECT-type E3 ubiquitin ligases can be distinguished from other subfamilies...

Descripción completa

Detalles Bibliográficos
Autores principales:	Delvecchio, Vincenza Simona, Fierro, Claudia, Giovannini, Sara, Melino, Gerry, Bernassola, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777521/ https://www.ncbi.nlm.nih.gov/pubmed/35201500 http://dx.doi.org/10.1007/s12672-021-00435-4

Ejemplares similares

Emerging roles of HECT‐type E3 ubiquitin ligases in autophagy regulation
por: Melino, Gerry, et al.
Publicado: (2019)

Screening for E3-Ubiquitin ligase inhibitors: challenges and opportunities
por: Landré, Vivien, et al.
Publicado: (2014)

High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy
por: Rossi, M, et al.
Publicado: (2014)

Emerging roles of the HECT E3 ubiquitin ligases in gastric cancer
por: Sun, Aiqin, et al.
Publicado: (2023)

Redefining the catalytic HECT domain boundaries for the HECT E3 ubiquitin ligase family
por: Kane, Emma I., et al.
Publicado: (2022)

Evolution of Plant HECT Ubiquitin Ligases
por: Marín, Ignacio
Publicado: (2013)

Activity‐Based Probes for HECT E3 Ubiquitin Ligases
por: Byrne, Robert, et al.
Publicado: (2017)

The Role of HECT E3 Ubiquitin Ligases in Colorectal Cancer
por: Sun, Aiqin, et al.
Publicado: (2023)

Origin and evolution of fungal HECT ubiquitin ligases
por: Marín, Ignacio
Publicado: (2018)

Animal HECT ubiquitin ligases: evolution and functional implications
por: Marín, Ignacio
Publicado: (2010)

HECT ubiquitin ligases as accessory proteins of the plant proteasome
por: Wang, Zhishuo, et al.
Publicado: (2022)

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
por: Riley, B.E., et al.
Publicado: (2013)

Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled
por: Mund, Thomas, et al.
Publicado: (2015)

Evidence of an Antimicrobial Peptide Signature Encrypted in HECT E3 Ubiquitin Ligases
por: Candido-Ferreira, Ivan Lavander, et al.
Publicado: (2017)

Structure and Function of HECT E3 Ubiquitin Ligases and their Role in Oxidative Stress
por: Qian, Hao, et al.
Publicado: (2020)

The Roles of NEDD4 Subfamily of HECT E3 Ubiquitin Ligases in Neurodevelopment and Neurodegeneration
por: Haouari, Shanez, et al.
Publicado: (2022)

HECT E3 Ligases: A Tale With Multiple Facets
por: Weber, Janine, et al.
Publicado: (2019)

A Genomic Survey of HECT Ubiquitin Ligases in Eukaryotes Reveals Independent Expansions of the HECT System in Several Lineages
por: Grau-Bové, Xavier, et al.
Publicado: (2013)

Regulating the human HECT E3 ligases
por: Sluimer, Jasper, et al.
Publicado: (2018)

The E3 ubiquitin ligase HectD3 attenuates cardiac hypertrophy and inflammation in mice
por: Rangrez, Ashraf Yusuf, et al.
Publicado: (2020)

Crystal structure of the catalytic C‐lobe of the HECT‐type ubiquitin ligase E6AP
por: Ries, Lena K., et al.
Publicado: (2020)

Genome-wide analysis of HECT E3 ubiquitin ligase gene family in Solanum lycopersicum
por: Sharma, Bhaskar, et al.
Publicado: (2021)

Proteasome-associated HECT-type ubiquitin ligase activity is required for plant immunity
por: Furniss, James J., et al.
Publicado: (2018)

A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence
por: Nair, Sethu C., et al.
Publicado: (2017)

Analysis of ubiquitin recognition by the HECT ligase E6AP provides insight into its linkage specificity
por: Ries, Lena K., et al.
Publicado: (2019)

HACE1 (HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1)
por: Cui, Feng, et al.
Publicado: (2012)

The Impact of the Ubiquitin System in the Pathogenesis of Squamous Cell Carcinomas
por: Gatti, Veronica, et al.
Publicado: (2020)

Hippo Stabilises Its Adaptor Salvador by Antagonising the HECT Ubiquitin Ligase Herc4
por: Aerne, Birgit L., et al.
Publicado: (2015)

The HECT domain ubiquitin ligase HUWE1 targets unassembled soluble proteins for degradation
por: Xu, Yue, et al.
Publicado: (2016)

Substrate clustering potently regulates the activity of WW-HECT domain–containing ubiquitin ligases
por: Mund, Thomas, et al.
Publicado: (2018)

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation
por: Maspero, Elena, et al.
Publicado: (2011)

Hect E3 ubiquitin ligase Tom1 controls Dia2 degradation during the cell cycle
por: Kim, Dong-Hwan, et al.
Publicado: (2012)

Molecular Evolution, Neurodevelopmental Roles and Clinical Significance of HECT-Type UBE3 E3 Ubiquitin Ligases
por: Ambrozkiewicz, Mateusz C., et al.
Publicado: (2020)

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5
por: Flack, Joshua E., et al.
Publicado: (2017)

HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway
por: Martin-Serrano, Juan, et al.
Publicado: (2005)

Selective compounds enhance osteoblastic activity by targeting HECT domain of ubiquitin ligase Smurf1
por: Zhang, Yuan, et al.
Publicado: (2016)

Developing Small‐Molecule Inhibitors of HECT‐Type Ubiquitin Ligases for Therapeutic Applications: Challenges and Opportunities
por: Chen, Dan, et al.
Publicado: (2018)

Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe
por: Nair, Rahul M., et al.
Publicado: (2021)

Inhibition of HECT E3 ligases as potential therapy for COVID-19
por: Novelli, Giuseppe, et al.
Publicado: (2021)

The Role of HECT-Type E3 Ligase in the Development of Cardiac Disease
por: Goto, Jun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6271tke7fqngnk9kqh8fc7nllu