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Caffeic acid phenethyl ester (CAPE) confers wild type p53 function in p53(Y220C) mutant: bioinformatics and experimental evidence

Mutations in the tumor suppressor protein p53 is a prevalent feature in majority of cancers resulting in inactivation of its activities related to control of cell cycle progression and proliferation. p53(Y220C) is one of the common hotspot mutations that causes decrease in its thermodynamic stabilit...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Navaneethan, Dhanjal, Jaspreet Kaur, Sari, Anissa Nofita, Ishida, Yoshiyuki, Terao, Keiji, Kaul, Sunil C., Sundar, Durai, Wadhwa, Renu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777538/
https://www.ncbi.nlm.nih.gov/pubmed/35201513
http://dx.doi.org/10.1007/s12672-021-00461-2