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Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review

Thyroid cancer’s incidence has increased in the last decades, and its diagnosis can be a challenge. Further and complementary testing based in biochemical alterations may be important to correctly identify thyroid cancer and prevent unnecessary surgery. Fourier-transform infrared (FTIR) spectroscopy...

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Autores principales: Neto, Vanessa, Esteves-Ferreira, Sara, Inácio, Isabel, Alves, Márcia, Dantas, Rosa, Almeida, Idália, Guimarães, Joana, Azevedo, Teresa, Nunes, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777789/
https://www.ncbi.nlm.nih.gov/pubmed/35050174
http://dx.doi.org/10.3390/metabo12010053
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author Neto, Vanessa
Esteves-Ferreira, Sara
Inácio, Isabel
Alves, Márcia
Dantas, Rosa
Almeida, Idália
Guimarães, Joana
Azevedo, Teresa
Nunes, Alexandra
author_facet Neto, Vanessa
Esteves-Ferreira, Sara
Inácio, Isabel
Alves, Márcia
Dantas, Rosa
Almeida, Idália
Guimarães, Joana
Azevedo, Teresa
Nunes, Alexandra
author_sort Neto, Vanessa
collection PubMed
description Thyroid cancer’s incidence has increased in the last decades, and its diagnosis can be a challenge. Further and complementary testing based in biochemical alterations may be important to correctly identify thyroid cancer and prevent unnecessary surgery. Fourier-transform infrared (FTIR) spectroscopy is a metabolomic technique that has already shown promising results in cancer metabolome analysis of neoplastic thyroid tissue, in the identification and classification of prostate tumor tissues and of breast carcinoma, among others. This work aims to gather and discuss published information on the ability of FTIR spectroscopy to be used in metabolomic studies of the thyroid, including discriminating between benign and malignant thyroid samples and grading and classifying different types of thyroid tumors.
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spelling pubmed-87777892022-01-22 Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review Neto, Vanessa Esteves-Ferreira, Sara Inácio, Isabel Alves, Márcia Dantas, Rosa Almeida, Idália Guimarães, Joana Azevedo, Teresa Nunes, Alexandra Metabolites Review Thyroid cancer’s incidence has increased in the last decades, and its diagnosis can be a challenge. Further and complementary testing based in biochemical alterations may be important to correctly identify thyroid cancer and prevent unnecessary surgery. Fourier-transform infrared (FTIR) spectroscopy is a metabolomic technique that has already shown promising results in cancer metabolome analysis of neoplastic thyroid tissue, in the identification and classification of prostate tumor tissues and of breast carcinoma, among others. This work aims to gather and discuss published information on the ability of FTIR spectroscopy to be used in metabolomic studies of the thyroid, including discriminating between benign and malignant thyroid samples and grading and classifying different types of thyroid tumors. MDPI 2022-01-08 /pmc/articles/PMC8777789/ /pubmed/35050174 http://dx.doi.org/10.3390/metabo12010053 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Neto, Vanessa
Esteves-Ferreira, Sara
Inácio, Isabel
Alves, Márcia
Dantas, Rosa
Almeida, Idália
Guimarães, Joana
Azevedo, Teresa
Nunes, Alexandra
Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review
title Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review
title_full Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review
title_fullStr Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review
title_full_unstemmed Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review
title_short Metabolic Profile Characterization of Different Thyroid Nodules Using FTIR Spectroscopy: A Review
title_sort metabolic profile characterization of different thyroid nodules using ftir spectroscopy: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777789/
https://www.ncbi.nlm.nih.gov/pubmed/35050174
http://dx.doi.org/10.3390/metabo12010053
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