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Global Disparities in Hepatitis B Elimination—A Focus on Africa
In 2016, WHO member states at the World Health Assembly adopted a Global Health Sector Strategy that included a policy of eliminating viral hepatitis. Clear targets were established to assist in achieving this by 2030. The strategy, while achievable, has exposed existing global disparities in health...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777803/ https://www.ncbi.nlm.nih.gov/pubmed/35062286 http://dx.doi.org/10.3390/v14010082 |
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author | Sonderup, Mark W. Spearman, C. Wendy |
author_facet | Sonderup, Mark W. Spearman, C. Wendy |
author_sort | Sonderup, Mark W. |
collection | PubMed |
description | In 2016, WHO member states at the World Health Assembly adopted a Global Health Sector Strategy that included a policy of eliminating viral hepatitis. Clear targets were established to assist in achieving this by 2030. The strategy, while achievable, has exposed existing global disparities in healthcare systems and their ability to implement such policies. Compounding this, the regions with most disparity are also those where the hepatitis B prevalence and disease burden are the greatest. Foundational to hepatitis B elimination is the identification of both those with chronic infection and crucially pregnant women, and primary prevention through vaccination. Vaccination, including the birth dose and full three-dose coverage, is key, but complete mother-to-child transmission prevention includes reducing the maternal hepatitis B viral load in the third trimester where appropriate. Innovations and simplified tools exist in order to achieve elimination, but what is desperately required is the will to implement these strategies through the support of appropriate investment and funding. Without this, disparities will continue. |
format | Online Article Text |
id | pubmed-8777803 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87778032022-01-22 Global Disparities in Hepatitis B Elimination—A Focus on Africa Sonderup, Mark W. Spearman, C. Wendy Viruses Review In 2016, WHO member states at the World Health Assembly adopted a Global Health Sector Strategy that included a policy of eliminating viral hepatitis. Clear targets were established to assist in achieving this by 2030. The strategy, while achievable, has exposed existing global disparities in healthcare systems and their ability to implement such policies. Compounding this, the regions with most disparity are also those where the hepatitis B prevalence and disease burden are the greatest. Foundational to hepatitis B elimination is the identification of both those with chronic infection and crucially pregnant women, and primary prevention through vaccination. Vaccination, including the birth dose and full three-dose coverage, is key, but complete mother-to-child transmission prevention includes reducing the maternal hepatitis B viral load in the third trimester where appropriate. Innovations and simplified tools exist in order to achieve elimination, but what is desperately required is the will to implement these strategies through the support of appropriate investment and funding. Without this, disparities will continue. MDPI 2022-01-03 /pmc/articles/PMC8777803/ /pubmed/35062286 http://dx.doi.org/10.3390/v14010082 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sonderup, Mark W. Spearman, C. Wendy Global Disparities in Hepatitis B Elimination—A Focus on Africa |
title | Global Disparities in Hepatitis B Elimination—A Focus on Africa |
title_full | Global Disparities in Hepatitis B Elimination—A Focus on Africa |
title_fullStr | Global Disparities in Hepatitis B Elimination—A Focus on Africa |
title_full_unstemmed | Global Disparities in Hepatitis B Elimination—A Focus on Africa |
title_short | Global Disparities in Hepatitis B Elimination—A Focus on Africa |
title_sort | global disparities in hepatitis b elimination—a focus on africa |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777803/ https://www.ncbi.nlm.nih.gov/pubmed/35062286 http://dx.doi.org/10.3390/v14010082 |
work_keys_str_mv | AT sonderupmarkw globaldisparitiesinhepatitisbeliminationafocusonafrica AT spearmancwendy globaldisparitiesinhepatitisbeliminationafocusonafrica |