Monooxygenase- and Dioxygenase-Catalyzed Oxidative Dearomatization of Thiophenes by Sulfoxidation, cis-Dihydroxylation and Epoxidation

Enzymatic oxidations of thiophenes, including thiophene-containing drugs, are important for biodesulfurization of crude oil and drug metabolism of mono- and poly-cyclic thiophenes. Thiophene oxidative dearomatization pathways involve reactive metabolites, whose detection is important in the pharmace...

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Detalles Bibliográficos
Autores principales: Boyd, Derek R., Sharma, Narain D., Stevenson, Paul J., Hoering, Patrick, Allen, Christopher C. R., Dansette, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777831/
https://www.ncbi.nlm.nih.gov/pubmed/35055091
http://dx.doi.org/10.3390/ijms23020909

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