A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)

The COVID-19 pandemic has resulted in large numbers of patients requiring critical care management. With the established association between severe respiratory virus infection and invasive pulmonary aspergillosis (7.6% for COVID-19-associated pulmonary aspergillosis (CAPA)), the pandemic places a si...

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Autores principales: White, P. Lewis, Springer, Jan, Wise, Matt P., Einsele, Hermann, Löffler, Claudia, Seif, Michelle, Prommersberger, Sabrina, Backx, Matthijs, Löffler, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777907/
https://www.ncbi.nlm.nih.gov/pubmed/35050021
http://dx.doi.org/10.3390/jof8010081
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author White, P. Lewis
Springer, Jan
Wise, Matt P.
Einsele, Hermann
Löffler, Claudia
Seif, Michelle
Prommersberger, Sabrina
Backx, Matthijs
Löffler, Jürgen
author_facet White, P. Lewis
Springer, Jan
Wise, Matt P.
Einsele, Hermann
Löffler, Claudia
Seif, Michelle
Prommersberger, Sabrina
Backx, Matthijs
Löffler, Jürgen
author_sort White, P. Lewis
collection PubMed
description The COVID-19 pandemic has resulted in large numbers of patients requiring critical care management. With the established association between severe respiratory virus infection and invasive pulmonary aspergillosis (7.6% for COVID-19-associated pulmonary aspergillosis (CAPA)), the pandemic places a significant number of patients at potential risk from secondary invasive fungal disease. We described a case of CAPA with substantial supporting mycological evidence, highlighting the need to employ strategic diagnostic algorithms and weighted definitions to improve the accuracy in diagnosing CAPA.
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spelling pubmed-87779072022-01-22 A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence) White, P. Lewis Springer, Jan Wise, Matt P. Einsele, Hermann Löffler, Claudia Seif, Michelle Prommersberger, Sabrina Backx, Matthijs Löffler, Jürgen J Fungi (Basel) Case Report The COVID-19 pandemic has resulted in large numbers of patients requiring critical care management. With the established association between severe respiratory virus infection and invasive pulmonary aspergillosis (7.6% for COVID-19-associated pulmonary aspergillosis (CAPA)), the pandemic places a significant number of patients at potential risk from secondary invasive fungal disease. We described a case of CAPA with substantial supporting mycological evidence, highlighting the need to employ strategic diagnostic algorithms and weighted definitions to improve the accuracy in diagnosing CAPA. MDPI 2022-01-14 /pmc/articles/PMC8777907/ /pubmed/35050021 http://dx.doi.org/10.3390/jof8010081 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
White, P. Lewis
Springer, Jan
Wise, Matt P.
Einsele, Hermann
Löffler, Claudia
Seif, Michelle
Prommersberger, Sabrina
Backx, Matthijs
Löffler, Jürgen
A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)
title A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)
title_full A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)
title_fullStr A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)
title_full_unstemmed A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)
title_short A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence)
title_sort clinical case of covid-19-associated pulmonary aspergillosis (capa), illustrating the challenges in diagnosis (despite overwhelming mycological evidence)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777907/
https://www.ncbi.nlm.nih.gov/pubmed/35050021
http://dx.doi.org/10.3390/jof8010081
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