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Therapeutic CFTR Correction Normalizes Systemic and Lung-Specific S1P Level Alterations Associated with Heart Failure

Heart failure (HF) is among the main causes of death worldwide. Alterations of sphingosine-1-phosphate (S1P) signaling have been linked to HF as well as to target organ damage that is often associated with HF. S1P’s availability is controlled by the cystic fibrosis transmembrane regulator (CFTR), wh...

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Detalles Bibliográficos
Autores principales:	Uhl, Franziska E., Vanherle, Lotte, Matthes, Frank, Meissner, Anja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777932/ https://www.ncbi.nlm.nih.gov/pubmed/35055052 http://dx.doi.org/10.3390/ijms23020866

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