Peptidoglycan-Free Bacterial Ghosts Confer Enhanced Protection against Yersinia pestis Infection

To develop a modern plague vaccine, we used hypo-endotoxic Yersinia pestis bacterial ghosts (BGs) with combinations of genes encoding the bacteriophage ɸX174 lysis-mediating protein E and/or holin-endolysin systems from λ or L-413C phages. Expression of the protein E gene resulted in the BGs that re...

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Detalles Bibliográficos
Autores principales: Dentovskaya, Svetlana V., Vagaiskaya, Anastasia S., Platonov, Mikhail E., Trunyakova, Alexandra S., Kotov, Sergei A., Krasil’nikova, Ekaterina A., Titareva, Galina M., Mazurina, Elizaveta M., Gapel’chenkova, Tat’yana V., Shaikhutdinova, Rima Z., Ivanov, Sergei A., Kombarova, Tat’yana I., Gerasimov, Vladimir N., Uversky, Vladimir N., Anisimov, Andrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777944/
https://www.ncbi.nlm.nih.gov/pubmed/35062712
http://dx.doi.org/10.3390/vaccines10010051

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