Cargando…

Tracking Radiolabeled Endothelial Microvesicles Predicts Their Therapeutic Efficacy: A Proof-of-Concept Study in Peripheral Ischemia Mouse Model Using SPECT/CT Imaging

Microvesicles, so-called endothelial large extracellular vesicles (LEVs), are of great interest as biological markers and cell-free biotherapies in cardiovascular and oncologic diseases. However, their therapeutic perspectives remain limited due to the lack of reliable data regarding their systemic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giraud, Romain, Moyon, Anaïs, Simoncini, Stéphanie, Duchez, Anne-Claire, Nail, Vincent, Chareyre, Corinne, Bouhlel, Ahlem, Balasse, Laure, Fernandez, Samantha, Vallier, Loris, Hache, Guillaume, Sabatier, Florence, Dignat-George, Françoise, Lacroix, Romaric, Guillet, Benjamin, Garrigue, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778059/ https://www.ncbi.nlm.nih.gov/pubmed/35057018 http://dx.doi.org/10.3390/pharmaceutics14010121

Ejemplares similares

Succinate Injection Rescues Vasculature and Improves Functional Recovery Following Acute Peripheral Ischemia in Rodents: A Multimodal Imaging Study
por: Moyon, Anaïs, et al.
Publicado: (2021)

Design and preclinical evaluation of a novel apelin-based PET radiotracer targeting APJ receptor for molecular imaging of angiogenesis
por: Louis, Béatrice, et al.
Publicado: (2023)

Comparison of a New (68)Ga-Radiolabelled PET Imaging Agent sCD146 and RGD Peptide for In Vivo Evaluation of Angiogenesis in Mouse Model of Myocardial Infarction
por: Moyon, Anaïs, et al.
Publicado: (2021)

Sublingual Atropine Administration as a Tool to Decrease Salivary Glands’ PSMA-Ligand Uptake: A Preclinical Proof of Concept Study Using [(68)Ga]Ga-PSMA-11
por: Nail, Vincent, et al.
Publicado: (2022)

Early prediction of revascularisation by angiomotin-targeting positron emission tomography
por: Moyon, Anais, et al.
Publicado: (2018)

Extracellular Vesicles in Angiogenesis
por: Todorova, Dilyana, et al.
Publicado: (2017)

A new assay to evaluate microvesicle plasmin generation capacity: validation in disease with fibrinolysis imbalance
por: Cointe, Sylvie, et al.
Publicado: (2018)

A new strategy to count and sort neutrophil‐derived extracellular vesicles: Validation in infectious disorders
por: Bonifay, Amandine, et al.
Publicado: (2022)

Stem cell properties of peripheral blood endothelial progenitors are stimulated by soluble CD146 via miR-21: potential use in autologous cell therapy
por: Essaadi, Amel, et al.
Publicado: (2018)

A Comprehensive Review of Non-Covalent Radiofluorination Approaches Using Aluminum [(18)F]fluoride: Will [(18)F]AlF Replace (68)Ga for Metal Chelate Labeling?
por: Fersing, Cyril, et al.
Publicado: (2019)

Have you looked for “stranger things” in your automated PET dose dispensing system? A process and operators qualification scheme
por: Martin, Tristan, et al.
Publicado: (2019)

Radiolabelling of Extracellular Vesicles for PET and SPECT imaging
por: Khan, Azalea A., et al.
Publicado: (2021)

Rapid nanobody-based imaging of mesothelin expressing malignancies compatible with blocking therapeutic antibodies
por: Benloucif, Abdennour, et al.
Publicado: (2023)

Long‐Term Recovery After Endothelial Colony‐Forming Cells or Human Umbilical Cord Blood Cells Administration in a Rat Model of Neonatal Hypoxic‐Ischemic Encephalopathy
por: Grandvuillemin, Isabelle, et al.
Publicado: (2017)

Methods for Radiolabelling Nanoparticles: SPECT Use (Part 1)
por: Varani, Michela, et al.
Publicado: (2022)

Iodine-125 radiolabeling of silver nanoparticles for in vivo SPECT imaging
por: Chrastina, Adrian, et al.
Publicado: (2010)

Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECT
por: Zhou, Yang, et al.
Publicado: (2011)

SPECT/CT with radiolabeled somatostatin analogues in the evaluation of systemic granulomatous infections
por: Monteiro, Paulo Henrique Silva, et al.
Publicado: (2017)

Radiolabeled Small Molecule Protein Kinase Inhibitors for Imaging with PET or SPECT
por: Hicks, Justin W., et al.
Publicado: (2010)

Radiolabeled Silicon-Rhodamines as Bimodal PET/SPECT-NIR Imaging Agents
por: Kanagasundaram, Thines, et al.
Publicado: (2021)

Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging
por: Gawne, Peter J., et al.
Publicado: (2022)

Biogenesis of Pro-senescent Microparticles by Endothelial Colony Forming Cells from Premature Neonates is driven by SIRT1-Dependent Epigenetic Regulation of MKK6
por: Simoncini, Stéphanie, et al.
Publicado: (2017)

Extracellular vesicles from T cells overexpress miR-146b-5p in HIV-1 infection and repress endothelial activation
por: Balducci, Estelle, et al.
Publicado: (2019)

A novel anti-CD146 antibody specifically targets cancer cells by internalizing the molecule
por: Nollet, Marie, et al.
Publicado: (2017)

Biodistribution of (68/67)Ga-Radiolabeled Sphingolipid Nanoemulsions by PET and SPECT Imaging
por: Díez-Villares, Sandra, et al.
Publicado: (2021)

Radiolabeled Risperidone microSPECT/CT Imaging for Intranasal Implant Studies Development
por: Simón, Jon Ander, et al.
Publicado: (2023)

Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors
por: Garrigue, Philippe, et al.
Publicado: (2018)

Maintenance chemotherapy in children with ALL exerts metronomic-like thrombospondin-1 associated anti-endothelial effect
por: Andre, Nicolas, et al.
Publicado: (2015)

Radiolabeled cCPE Peptides for SPECT Imaging of Claudin-4 Overexpression in Pancreatic Cancer
por: Torres, Julia Baguña, et al.
Publicado: (2020)

Radiolabeled Iron Oxide Nanoparticles as Dual Modality Contrast Agents in SPECT/MRI and PET/MRI
por: Karageorgou, Maria-Argyro, et al.
Publicado: (2023)

Phenotyping of Macrophages After Radiolabeling and Safety of Intra-arterial Transplantation Assessed by SPECT/CT and MRI
por: Friberger, Ida, et al.
Publicado: (2023)

Circulating microvesicles correlate with radiation proctitis complication after radiotherapy
por: Ribault, Alexandre, et al.
Publicado: (2023)

Renal uptake of different radiolabelled peptides is mediated by megalin: SPECT and biodistribution studies in megalin-deficient mice
por: Vegt, Erik, et al.
Publicado: (2010)

Thromboxane–prostaglandin receptor antagonist, terutroban, prevents neurovascular events after subarachnoid haemorrhage: a nanoSPECT study in rats
por: Lagier, David, et al.
Publicado: (2019)

Radiolabeling and Preliminary Evaluation of (99m)Tc-Labeled DNA Cube Nanoparticles as Potential Tracers for SPECT Imaging
por: Duan, Xiaoyan, et al.
Publicado: (2021)

Adipose-Derived Stem Cells from Systemic Sclerosis Patients Maintain Pro-Angiogenic and Antifibrotic Paracrine Effects In Vitro
por: VELIER, Mélanie, et al.
Publicado: (2019)

Radiolabeling and Preliminary Evaluation of (99m)Tc-Labeled DNA Cube Nanoparticles as Potential Tracers for SPECT Imaging [Corrigendum]
Publicado: (2022)

Female AhR Knockout Mice Develop a Minor Renal Insufficiency in an Adenine-Diet Model of Chronic Kidney Disease
por: Makhloufi, Camélia, et al.
Publicado: (2020)

Development and Validation of a Fully GMP-Compliant Process for Manufacturing Stromal Vascular Fraction: A Cost-Effective Alternative to Automated Methods
por: François, Pauline, et al.
Publicado: (2020)

Bisphosphonate-Anchored PEGylation and Radiolabeling of Superparamagnetic Iron Oxide: Long-Circulating Nanoparticles for in Vivo Multimodal (T1 MRI-SPECT) Imaging
por: Sandiford, Lydia, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_nmec4uk4noiulsm8f2omdui3s8