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Genome-Wide CRISPR/Cas9-Based Screening for Deubiquitinase Subfamily Identifies Ubiquitin-Specific Protease 11 as a Novel Regulator of Osteogenic Differentiation

The osteoblast differentiation capacity of mesenchymal stem cells must be tightly regulated, as inadequate bone mineralization can lead to osteoporosis, and excess bone formation can cause the heterotopic ossification of soft tissues. The balanced protein level of Msh homeobox 1 (MSX1) is critical d...

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Detalles Bibliográficos
Autores principales:	Kaushal, Kamini, Tyagi, Apoorvi, Karapurkar, Janardhan Keshav, Kim, Eun-Jung, Tanguturi, Parthasaradhireddy, Kim, Kye-Seong, Jung, Han-Sung, Ramakrishna, Suresh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778097/ https://www.ncbi.nlm.nih.gov/pubmed/35055037 http://dx.doi.org/10.3390/ijms23020856

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