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Development and Validation of an Analytical HPLC Method to Assess Chemical and Radiochemical Purity of [(68)Ga]Ga-NODAGA-Exendin-4 Produced by a Fully Automated Method

Background: Glucagon-like peptide 1 receptor (GLP-1R) is preferentially expressed in pancreatic islets, especially in β-cells, and highly expressed in human insulinomas and gastrinomas. In recent years several GLP-1R–avid radioligands have been developed to image insulin-secreting tumors or to provi...

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Detalles Bibliográficos
Autores principales:	Migliari, Silvia, Sammartano, Antonino, Boss, Marti, Gotthardt, Martin, Scarlattei, Maura, Baldari, Giorgio, Silva, Claudia, Bonadonna, Riccardo C., Ruffini, Livia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778103/ https://www.ncbi.nlm.nih.gov/pubmed/35056858 http://dx.doi.org/10.3390/molecules27020543

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