The Downregulation of Both Giant HERCs, HERC1 and HERC2, Is an Unambiguous Feature of Chronic Myeloid Leukemia, and HERC1 Levels Are Associated with Leukemic Cell Differentiation

Large HERC E3 ubiquitin ligase family members, HERC1 and HERC2, are staggeringly complex proteins that can intervene in a wide range of biological processes, such as cell proliferation, DNA repair, neurodevelopment, and inflammation. Therefore, mutations or dysregulation of large HERCs is associated...

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Detalles Bibliográficos
Autores principales: Ali, Muhammad Shahzad, Magnati, Stefano, Panuzzo, Cristina, Cilloni, Daniela, Saglio, Giuseppe, Pergolizzi, Barbara, Bracco, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778248/
https://www.ncbi.nlm.nih.gov/pubmed/35054018
http://dx.doi.org/10.3390/jcm11020324

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