Cargando…

Elovanoids Counteract Inflammatory Signaling, Autophagy, Endoplasmic Reticulum Stress, and Senescence Gene Programming in Human Nasal Epithelial Cells Exposed to Allergens

To contribute to further understanding the cellular and molecular complexities of inflammatory-immune responses in allergic disorders, we have tested the pro-homeostatic elovanoids (ELV) in human nasal epithelial cells (HNEpC) in culture challenged by several allergens. ELV are novel bioactive lipid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Resano, Alfredo, Bhattacharjee, Surjyadipta, Barajas, Miguel, Do, Khanh V., Aguado-Jiménez, Roberto, Rodríguez, David, Palacios, Ricardo, Bazán, Nicolás G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778361/ https://www.ncbi.nlm.nih.gov/pubmed/35057008 http://dx.doi.org/10.3390/pharmaceutics14010113

Ejemplares similares

Elovanoids are neural resiliency epigenomic regulators targeting histone modifications, DNA methylation, tau phosphorylation, telomere integrity, senescence programming, and dendrite integrity
por: Bazan, Nicolas, et al.
Publicado: (2023)

Elovanoids counteract oligomeric β-amyloid-induced gene expression and protect photoreceptors
por: Do, Khanh V., et al.
Publicado: (2019)

Elovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrity
por: Jun, Bokkyoo, et al.
Publicado: (2017)

Elovanoids downregulate SARS-CoV-2 cell-entry, canonical mediators and enhance protective signaling in human alveolar cells
por: Calandria, Jorgelina M., et al.
Publicado: (2021)

Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury
por: Bhattacharjee, Surjyadipta, et al.
Publicado: (2017)

Elovanoid-N32 or RvD6-isomer decrease ACE2 and binding of S protein RBD after injury or INFγ in the eye
por: Pham, Thang L., et al.
Publicado: (2020)

Overview of how N32 and N34 elovanoids sustain sight by protecting retinal pigment epithelial cells and photoreceptors
por: Bazan, Nicolas G.
Publicado: (2021)

Integrated inflammatory signaling landscape response after delivering Elovanoid free-fatty-acid precursors leading to experimental stroke neuroprotection
por: Reid, Madigan M., et al.
Publicado: (2023)

Targeting the Endoplasmic Reticulum Unfolded Protein Response to Counteract the Oxidative Stress-Induced Endothelial Dysfunction
por: Amodio, Giuseppina, et al.
Publicado: (2018)

Taurine represses age‐associated gut hyperplasia in Drosophila via counteracting endoplasmic reticulum stress
por: Du, Gang, et al.
Publicado: (2021)

ERp29 counteracts the suppression of malignancy mediated by endoplasmic reticulum stress and promotes the metastasis of colorectal cancer
por: Guo, Lili, et al.
Publicado: (2019)

Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis
por: Griffin, Haven, et al.
Publicado: (2022)

Senescent Changes and Endoplasmic Reticulum Stress May Be Involved in the Pathogenesis of Missed Miscarriage
por: Tang, Yunhui, et al.
Publicado: (2021)

THE ENDOPLASMIC RETICULUM
por: Palade, George E.
Publicado: (1956)

TGF-β1 Activates Nasal Fibroblasts through the Induction of Endoplasmic Reticulum Stress
por: Shin, Jae-Min, et al.
Publicado: (2020)

PPARgamma Deficiency Counteracts Thymic Senescence
por: Ernszt, David, et al.
Publicado: (2017)

Induction of Premature Cell Senescence Stimulated by High Doses of Antioxidants Is Mediated by Endoplasmic Reticulum Stress
por: Lyublinskaya, Olga, et al.
Publicado: (2021)

Construction of the endoplasmic reticulum
Publicado: (1989)

Docosahexaenoic acid counteracts palmitate‐induced endoplasmic reticulum stress in C2C12 myotubes: Impact on muscle atrophy
por: Woodworth‐Hobbs, Myra E., et al.
Publicado: (2017)

HYPERTROPHY OF GRANULAR ENDOPLASMIC RETICULUM AND ANNULATE LAMELLAE IN EARLE'S L CELLS EXPOSED TO VINBLASTINE SULFATE
por: Krishan, Awtar, et al.
Publicado: (1968)

Identification of Two Regions in Apolipoprotein B100 that are Exposed on the Cytosolic Side of the Endoplasmic Reticulum Membrane
por: Du, Xiaobo, et al.
Publicado: (1998)

Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum
por: Trentzsch, Marcus, et al.
Publicado: (2020)

Mitochondrial Protein Akap1 Deletion Exacerbates Endoplasmic Reticulum Stress in Mice Exposed to Hyperoxia
por: Sidramagowda Patil, Sahebgowda, et al.
Publicado: (2022)

SIRT3 consolidates heterochromatin and counteracts senescence
por: Diao, Zhiqing, et al.
Publicado: (2021)

FTO stabilizes MIS12 and counteracts senescence
por: Zhang, Sheng, et al.
Publicado: (2022)

Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence
por: Pan, Jin-Xiu, et al.
Publicado: (2021)

Paxlovid accelerates cartilage degeneration and senescence through activating endoplasmic reticulum stress and interfering redox homeostasis
por: Kong, Keyu, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress and Cancer
por: Yadav, Raj Kumar, et al.
Publicado: (2014)

Regulation of endoplasmic reticulum functions
por: Namba, Takushi
Publicado: (2015)

Endoplasmic reticulum stress and apoptosis
por: Faitova, Jitka, et al.
Publicado: (2006)

Autophagic degradation of the endoplasmic reticulum
por: NAKATOGAWA, Hitoshi
Publicado: (2020)

Salubrinal Exposes Anticancer Properties in Inflammatory Breast Cancer Cells by Manipulating the Endoplasmic Reticulum Stress Pathway
por: Alsterda, Andrew, et al.
Publicado: (2021)

Endoplasmic Reticulum (ER) Stress and Its Role in Pancreatic β-Cell Dysfunction and Senescence in Type 2 Diabetes
por: Lee, Ji-Hye, et al.
Publicado: (2022)

Stress granules counteract senescence by sequestration of PAI‐1
por: Omer, Amr, et al.
Publicado: (2018)

ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin
por: Hu, Huifang, et al.
Publicado: (2020)

Correction to ‘SIRT3 consolidates heterochromatin and counteracts senescence’
por: Diao, Zhiqing, et al.
Publicado: (2021)

Nasal allergen provocation test in nasal polyposis with and without allergy
por: Calus, Lien, et al.
Publicado: (2013)

Effects of Nasal Corticosteroids on Boosts of Systemic Allergen-Specific IgE Production Induced by Nasal Allergen Exposure
por: Egger, Cornelia, et al.
Publicado: (2015)

Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model
por: Lay, Angelina J., et al.
Publicado: (2022)

Nasal commensal Staphylococcus epidermidis counteracts influenza virus
por: Chen, Hui-Wen, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_psv6oa3og4rksbck4msu2rh6vb