A systematic review of genotypes and serogroups of African swine fever virus

African swine fever virus (ASFV) is the causative agent of African swine fever (ASF). The virus causes an acute highly hemorrhagic disease in domestic pigs, with high mortality. Although the overall genome mutation rate of ASFV, a large DNA virus, is relatively low, ASFV exhibits genetic and antigen...

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Autores principales: Qu, Hailong, Ge, Shengqiang, Zhang, Yongqiang, Wu, Xiaodong, Wang, Zhiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778497/
https://www.ncbi.nlm.nih.gov/pubmed/35061204
http://dx.doi.org/10.1007/s11262-021-01879-0
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author Qu, Hailong
Ge, Shengqiang
Zhang, Yongqiang
Wu, Xiaodong
Wang, Zhiliang
author_facet Qu, Hailong
Ge, Shengqiang
Zhang, Yongqiang
Wu, Xiaodong
Wang, Zhiliang
author_sort Qu, Hailong
collection PubMed
description African swine fever virus (ASFV) is the causative agent of African swine fever (ASF). The virus causes an acute highly hemorrhagic disease in domestic pigs, with high mortality. Although the overall genome mutation rate of ASFV, a large DNA virus, is relatively low, ASFV exhibits genetic and antigenic diversity. ASFV can be classified into 24 genotypes on the basis of the B646L gene. Cross-protected ASFV strains can be divided into eight serogroups on the basis of antibody-mediated hemadsorption inhibition. Here, we review research progress on ASFV genotyping and serogrouping, and explain how this information assists in the rapid identification of virus origin during ASF outbreaks and will aid in the development of ASF vaccines.
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spelling pubmed-87784972022-01-21 A systematic review of genotypes and serogroups of African swine fever virus Qu, Hailong Ge, Shengqiang Zhang, Yongqiang Wu, Xiaodong Wang, Zhiliang Virus Genes Review Paper African swine fever virus (ASFV) is the causative agent of African swine fever (ASF). The virus causes an acute highly hemorrhagic disease in domestic pigs, with high mortality. Although the overall genome mutation rate of ASFV, a large DNA virus, is relatively low, ASFV exhibits genetic and antigenic diversity. ASFV can be classified into 24 genotypes on the basis of the B646L gene. Cross-protected ASFV strains can be divided into eight serogroups on the basis of antibody-mediated hemadsorption inhibition. Here, we review research progress on ASFV genotyping and serogrouping, and explain how this information assists in the rapid identification of virus origin during ASF outbreaks and will aid in the development of ASF vaccines. Springer US 2022-01-21 2022 /pmc/articles/PMC8778497/ /pubmed/35061204 http://dx.doi.org/10.1007/s11262-021-01879-0 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Paper
Qu, Hailong
Ge, Shengqiang
Zhang, Yongqiang
Wu, Xiaodong
Wang, Zhiliang
A systematic review of genotypes and serogroups of African swine fever virus
title A systematic review of genotypes and serogroups of African swine fever virus
title_full A systematic review of genotypes and serogroups of African swine fever virus
title_fullStr A systematic review of genotypes and serogroups of African swine fever virus
title_full_unstemmed A systematic review of genotypes and serogroups of African swine fever virus
title_short A systematic review of genotypes and serogroups of African swine fever virus
title_sort systematic review of genotypes and serogroups of african swine fever virus
topic Review Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778497/
https://www.ncbi.nlm.nih.gov/pubmed/35061204
http://dx.doi.org/10.1007/s11262-021-01879-0
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