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Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants
Background and Objectives: Preterm infants are at higher risk of neurodevelopmental impairment both at preschool and school ages, even in the absence of major neurological deficits. The early identification of children at risk is essential for early intervention with rehabilitation to optimize poten...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778540/ https://www.ncbi.nlm.nih.gov/pubmed/35056441 http://dx.doi.org/10.3390/medicina58010133 |
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author | Romeo, Domenico M. Ricci, Martina Mirra, Federica Venezia, Ilaria Mallardi, Maria Pede, Elisa Mercuri, Eugenio |
author_facet | Romeo, Domenico M. Ricci, Martina Mirra, Federica Venezia, Ilaria Mallardi, Maria Pede, Elisa Mercuri, Eugenio |
author_sort | Romeo, Domenico M. |
collection | PubMed |
description | Background and Objectives: Preterm infants are at higher risk of neurodevelopmental impairment both at preschool and school ages, even in the absence of major neurological deficits. The early identification of children at risk is essential for early intervention with rehabilitation to optimize potential outcomes during school years. The aim of our study is to assess cognitive outcomes at preschool age in a cohort of low-risk very preterm infants, previously studied at 12 and 24 months using the Griffiths scales. Materials and Methods: Sixty-six low-risk very preterm infants born at a gestational age of <32 weeks were assessed at 12 and 24 months corrected age using the Griffiths Mental Development Scales (second edition) and at preschool age with the Wechsler Preschool and Primary Scales of Intelligence (third edition) (WPPSI-III). Results: At 12 and 24 months and at preschool age, low-risk very preterm infants showed scores within normal ranges with similar scores in males and females. A statistically significant correlation was observed in the general developmental quotient between 12 and 24 months; a further significant correlation was observed between the early cognitive assessments and those performed at preschool age, with a better correlation using the assessments at 24 months. Conclusion: The present study showed a favourable trajectory of cognitive development in low-risk very preterm infants, from 12 months to preschool age. |
format | Online Article Text |
id | pubmed-8778540 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87785402022-01-22 Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants Romeo, Domenico M. Ricci, Martina Mirra, Federica Venezia, Ilaria Mallardi, Maria Pede, Elisa Mercuri, Eugenio Medicina (Kaunas) Article Background and Objectives: Preterm infants are at higher risk of neurodevelopmental impairment both at preschool and school ages, even in the absence of major neurological deficits. The early identification of children at risk is essential for early intervention with rehabilitation to optimize potential outcomes during school years. The aim of our study is to assess cognitive outcomes at preschool age in a cohort of low-risk very preterm infants, previously studied at 12 and 24 months using the Griffiths scales. Materials and Methods: Sixty-six low-risk very preterm infants born at a gestational age of <32 weeks were assessed at 12 and 24 months corrected age using the Griffiths Mental Development Scales (second edition) and at preschool age with the Wechsler Preschool and Primary Scales of Intelligence (third edition) (WPPSI-III). Results: At 12 and 24 months and at preschool age, low-risk very preterm infants showed scores within normal ranges with similar scores in males and females. A statistically significant correlation was observed in the general developmental quotient between 12 and 24 months; a further significant correlation was observed between the early cognitive assessments and those performed at preschool age, with a better correlation using the assessments at 24 months. Conclusion: The present study showed a favourable trajectory of cognitive development in low-risk very preterm infants, from 12 months to preschool age. MDPI 2022-01-16 /pmc/articles/PMC8778540/ /pubmed/35056441 http://dx.doi.org/10.3390/medicina58010133 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Romeo, Domenico M. Ricci, Martina Mirra, Federica Venezia, Ilaria Mallardi, Maria Pede, Elisa Mercuri, Eugenio Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants |
title | Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants |
title_full | Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants |
title_fullStr | Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants |
title_full_unstemmed | Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants |
title_short | Longitudinal Cognitive Assessment in Low-Risk Very Preterm Infants |
title_sort | longitudinal cognitive assessment in low-risk very preterm infants |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778540/ https://www.ncbi.nlm.nih.gov/pubmed/35056441 http://dx.doi.org/10.3390/medicina58010133 |
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