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SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa
Reverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778549/ https://www.ncbi.nlm.nih.gov/pubmed/35062324 http://dx.doi.org/10.3390/v14010120 |
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author | Koeppel, Katja Natalie Mendes, Adriano Strydom, Amy Rotherham, Lia Mulumba, Misheck Venter, Marietjie |
author_facet | Koeppel, Katja Natalie Mendes, Adriano Strydom, Amy Rotherham, Lia Mulumba, Misheck Venter, Marietjie |
author_sort | Koeppel, Katja Natalie |
collection | PubMed |
description | Reverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species will mitigate the risk to humans and wildlife occurring in Africa. Here we report infection of an exotic puma (July 2020) and three African lions (July 2021) in the same private zoo in Johannesburg, South Africa. One Health genomic surveillance identified transmission of a Delta variant from a zookeeper to the three lions, similar to those circulating in humans in South Africa. One lion developed pneumonia while the other cases had mild infection. Both the puma and lions remained positive for SARS-CoV-2 RNA for up to 7 weeks. |
format | Online Article Text |
id | pubmed-8778549 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87785492022-01-22 SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa Koeppel, Katja Natalie Mendes, Adriano Strydom, Amy Rotherham, Lia Mulumba, Misheck Venter, Marietjie Viruses Article Reverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species will mitigate the risk to humans and wildlife occurring in Africa. Here we report infection of an exotic puma (July 2020) and three African lions (July 2021) in the same private zoo in Johannesburg, South Africa. One Health genomic surveillance identified transmission of a Delta variant from a zookeeper to the three lions, similar to those circulating in humans in South Africa. One lion developed pneumonia while the other cases had mild infection. Both the puma and lions remained positive for SARS-CoV-2 RNA for up to 7 weeks. MDPI 2022-01-11 /pmc/articles/PMC8778549/ /pubmed/35062324 http://dx.doi.org/10.3390/v14010120 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Koeppel, Katja Natalie Mendes, Adriano Strydom, Amy Rotherham, Lia Mulumba, Misheck Venter, Marietjie SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
title | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
title_full | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
title_fullStr | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
title_full_unstemmed | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
title_short | SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa |
title_sort | sars-cov-2 reverse zoonoses to pumas and lions, south africa |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778549/ https://www.ncbi.nlm.nih.gov/pubmed/35062324 http://dx.doi.org/10.3390/v14010120 |
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