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Detection of Benzo[a]pyrene Diol Epoxide Adducts to Histidine and Lysine in Serum Albumin In Vivo by High-Resolution-Tandem Mass Spectrometry

Electrophilic diol epoxide metabolites are involved in the carcinogenicity of benzo[a]pyrene, one of the widely studied polycyclic aromatic hydrocarbons (PAHs). The exposure of humans to this PAH can be assessed by measuring stable blood protein adducts, such as to histidine and lysine in serum albu...

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Detalles Bibliográficos
Autores principales: Zurita, Javier, Motwani, Hitesh V., Ilag, Leopold L., Souliotis, Vassilis L., Kyrtopoulos, Soterios A., Nilsson, Ulrika, Törnqvist, Margareta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778559/
https://www.ncbi.nlm.nih.gov/pubmed/35051069
http://dx.doi.org/10.3390/toxics10010027