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Modelling Metabolic Shifts during Cardiomyocyte Differentiation, Iron Deficiency and Transferrin Rescue Using Human Pluripotent Stem Cells

Cardiomyocytes rely on specialised metabolism to meet the high energy demand of the heart. During heart development, metabolism matures and shifts from the predominant utilisation of glycolysis and glutamine oxidation towards lactate and fatty acid oxidation. Iron deficiency (ID) leads to cellular m...

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Detalles Bibliográficos
Autores principales:	Johnson, Benjamin B., Reinhold, Johannes, Holmes, Terri L., Moore, Jamie A., Cowell, Verity, Bernardo, Andreia S., Rushworth, Stuart A., Vassiliou, Vassilios, Smith, James G. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778576/ https://www.ncbi.nlm.nih.gov/pubmed/35050131 http://dx.doi.org/10.3390/metabo12010009

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