Chronic Pelvic Osteomyelitis: Case Report of a Rare Complication of Bone Marrow Biopsy

Osteomyelitis commonly involves the long bones, with pelvic involvement uncommon. We report the case of a 50-year-old male who, following a bone marrow biopsy that diagnosed him with non-Hodgkin’s lymphoma, had persistent complaints of fever, swelling, and pain over the biopsy site. Pus cultures revealed growth of methicillin-resistant Staphylococcus aureus (MRSA), with computed tomography and magnetic resonance imaging of the pelvis revealing features of osteomyelitis of the right ilium. He was managed conservatively with antibiotics. On the last follow-up, he had just recovered from another flare of the infection. Bone marrow biopsy is a common tool in the hematologist's inventory. It is quite safe, with complications reported in less than 0.1% of all cases. Osteomyelitis of the pelvis following this is exceedingly rare; to our knowledge, only two prior such cases have been reported. Pelvic osteomyelitis is characterized by poorly defined hip pain, limited range of motion, and difficulty with ambulation. In case of intractable hip or buttock pain following a bone marrow biopsy, osteomyelitis of the pelvis must be considered in the differential diagnosis, and appropriate management must be begun. A multidisciplinary approach is required, with surgical debridement and appropriate antibiotics.