Synergetic protective effect of remote ischemic preconditioning and prolyl 4-hydroxylase inhibition in ischemic cardiac injury

It has been reported that hypoxia-inducible factor 1α (HIF-1α) serves a key role in the protective effect of remote ischemic preconditioning (RIP) in ischemia/reperfusion (I/R)-induced cardiac injury. Moreover, inhibition of prolyl 4-hydroxylase (PHD), an enzyme responsible for HIF-1α degradation, p...

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Detalles Bibliográficos
Autores principales: Yang, Juesheng, Xu, Jiajun, Tao, Lei, Wang, Shiyong, Xiang, Haiyan, Tang, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778658/
https://www.ncbi.nlm.nih.gov/pubmed/35029283
http://dx.doi.org/10.3892/mmr.2022.12596

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