TNF-α Activating Osteoclasts in Patients with Psoriatic Arthritis Enhances the Recruitment of Osteoclast Precursors: A Plausible Role of WNT5A-MCP-1 in Osteoclast Engagement in Psoriatic Arthritis

Psoriatic arthritis (PsA) results from joint destruction by osteoclasts. The promising efficacy of TNF-α blockage indicates its important role in osteoclastogenesis of PsA. WNT ligands actively regulate osteoclastogenesis. We investigated how WNT ligands activate osteoclasts amid the TNF-α milieu in...

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Detalles Bibliográficos
Autores principales: Lin, Shang-Hung, Ho, Ji-Chen, Li, Sung-Chou, Cheng, Yu-Wen, Hsu, Chung-Yuan, Chou, Wen-Yi, Hsiao, Chang-Chun, Lee, Chih-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778693/
https://www.ncbi.nlm.nih.gov/pubmed/35055107
http://dx.doi.org/10.3390/ijms23020921

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