Cargando…

HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma

The neural crest transcription factor BRN3A is essential for the proliferation and survival of melanoma cells. It is frequently expressed in melanoma but not in normal melanocytes or benign nevi. The mechanisms underlying the aberrant expression of BRN3A are unknown. Here, we investigated the epigen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heppt, Markus V., Wessely, Anja, Hornig, Eva, Kammerbauer, Claudia, Graf, Saskia A., Besch, Robert, French, Lars E., Matthies, Alexander, Kuphal, Silke, Kappelmann-Fenzl, Melanie, Bosserhoff, Anja K., Berking, Carola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778714/ https://www.ncbi.nlm.nih.gov/pubmed/35055045 http://dx.doi.org/10.3390/ijms23020849

Ejemplares similares

C-Jun drives melanoma progression in PTEN wild type melanoma cells
por: Kappelmann-Fenzl, Melanie, et al.
Publicado: (2019)

Knockdown of Lamin B1 and the Corresponding Lamin B Receptor Leads to Changes in Heterochromatin State and Senescence Induction in Malignant Melanoma
por: Lämmerhirt, Lisa, et al.
Publicado: (2022)

Amphiregulin Regulates Melanocytic Senescence
por: Pommer, Michaela, et al.
Publicado: (2021)

HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth
por: Liebig, Janika K., et al.
Publicado: (2020)

The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival
por: Hohenauer, Tobias, et al.
Publicado: (2013)

Impact of CYLD on chromatin structure and histone methylation in malignant melanoma
por: Schott, Mandy, et al.
Publicado: (2022)

Selective Induction of Cell Death in Melanoma Cell Lines through Targeting of Mcl-1 and A1
por: Senft, Daniela, et al.
Publicado: (2012)

UVB radiation represses CYLD expression in melanocytes
por: Kuphal, Silke, et al.
Publicado: (2017)

Loss of Gene Information: Discrepancies between RNA Sequencing, cDNA Microarray, and qRT-PCR
por: Rachinger, Nicole, et al.
Publicado: (2021)

How Neural Crest Transcription Factors Contribute to Melanoma Heterogeneity, Cellular Plasticity, and Treatment Resistance
por: Wessely, Anja, et al.
Publicado: (2021)

Alpha-Synuclein and Its Role in Melanocytes
por: Rachinger, Nicole, et al.
Publicado: (2022)

Complex Formation with Monomeric α-Tubulin and Importin 13 Fosters c-Jun Protein Stability and Is Required for c-Jun’s Nuclear Translocation and Activity
por: Kappelmann-Fenzl, Melanie, et al.
Publicado: (2019)

Functional Implication of Netrin Expression in Malignant Melanoma
por: Kaufmann, Simone, et al.
Publicado: (2009)

Evaluation of PD-L1 Expression and HPV Genotyping in Anal Squamous Cell Carcinoma
por: Wessely, Anja, et al.
Publicado: (2020)

The Role of Immune Checkpoint Blockade in Uveal Melanoma
por: Wessely, Anja, et al.
Publicado: (2020)

A previously unknown Argonaute 2 variant positively modulates the viability of melanoma cells
por: Linck-Paulus, Lisa, et al.
Publicado: (2022)

The neurotrophin Neuritin1 (cpg15) is involved in melanoma migration, attachment independent growth, and vascular mimicry
por: Bosserhoff, Anja Katrin, et al.
Publicado: (2016)

The Value of Total Body Photography for the Early Detection of Melanoma: A Systematic Review
por: Hornung, Annkathrin, et al.
Publicado: (2021)

Loss of CYLD accelerates melanoma development and progression in the Tg(Grm1) melanoma mouse model
por: de Jel, Miriam Martha, et al.
Publicado: (2019)

Targeted Therapy-Resistant Melanoma Cells Acquire Transcriptomic Similarities with Human Melanoblasts
por: Larribère, Lionel, et al.
Publicado: (2018)

The Quality of Practice Guidelines for Melanoma: A Methodologic Appraisal with the AGREE II and AGREE-REX Instruments
por: Steeb, Theresa, et al.
Publicado: (2020)

eImmunonkologie: Development and Launch of a Virtual Education Platform for the Immunotherapy of Cutaneous Neoplasms
por: Kaufmann, Matthias D., et al.
Publicado: (2022)

Sox9 regulates melanocytic fate decision of adult hair follicle stem cells
por: Stüfchen, Isabel, et al.
Publicado: (2023)

Immune Checkpoint Blockade in Advanced Cutaneous Squamous Cell Carcinoma: What Do We Currently Know in 2020?
por: Wessely, Anja, et al.
Publicado: (2020)

Spontaneous regression rates of actinic keratosis: a systematic review and pooled analysis of randomized controlled trials
por: Steeb, Theresa, et al.
Publicado: (2022)

Increasing Participation Rates in Germany’s Skin Cancer Screening Program (HELIOS): Protocol for a Mixed Methods Study
por: Steeb, Theresa, et al.
Publicado: (2021)

Opportunities to inform German residents about the possibility of skin cancer screening and to inform stakeholders to take appropriate actions: A qualitative approach
por: Steeb, Theresa, et al.
Publicado: (2023)

How to Assess the Efficacy of Interventions for Actinic Keratosis? A Review with a Focus on Long-Term Results
por: Steeb, Theresa, et al.
Publicado: (2021)

Patient Attitudes and Their Awareness Towards Skin Cancer–Related Apps: Cross-Sectional Survey
por: Steeb, Theresa, et al.
Publicado: (2019)

Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro
por: Zimmermann, Tom, et al.
Publicado: (2022)

Selenium-binding protein 1 is down-regulated in malignant melanoma
por: Schott, Mandy, et al.
Publicado: (2018)

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma
por: Massoumi, Ramin, et al.
Publicado: (2009)

Molecular Changes Induced in Melanoma by Cell Culturing in 3D Alginate Hydrogels
por: Kappelmann-Fenzl, Melanie, et al.
Publicado: (2021)

Experiences of In-Patients with Skin Cancer in a German University Hospital Setting: A Cross-Sectional Survey
por: Steeb, Theresa, et al.
Publicado: (2021)

A Systematic Review and Meta-Analysis of Interventions for Actinic Keratosis from Post-Marketing Surveillance Trials
por: Steeb, Theresa, et al.
Publicado: (2020)

A Critical Appraisal of Evidence- and Consensus-Based Guidelines for Actinic Keratosis
por: Wessely, Anja, et al.
Publicado: (2021)

In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-X(L) and Mcl-1 but in the absence of active BH3-only proteins
por: Senft, D, et al.
Publicado: (2015)

BRN2 expression increases anoikis resistance in melanoma
por: Pierce, Carly J., et al.
Publicado: (2020)

Conventional and three-dimensional photography as a tool to map distribution patterns of in-transit melanoma metastases on the lower extremity
por: Müller, Kilian, et al.
Publicado: (2023)

“I Feel I’m in Best Hands with You!”: A Survey of Patient Satisfaction in a German University Skin Cancer Centre
por: STEEB, Theresa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_urj68so53mejrjqm8vn1tvgq6j