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C-X-C receptor 7 agonist acts as a C-X-C motif chemokine ligand 12 inhibitor to ameliorate osteoclastogenesis and bone resorption

The C-X-C receptor (CXCR) 7 agonist, VUF11207, is a chemical compound that binds specifically to CXCR7, and negatively regulates C-X-C motif chemokine ligand 12 (CXCL12) and CXCR4-induced cellular events. Lipopolysaccharide (LPS) can induce inflammatory cytokines and pathological bone loss. LPS also...

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Detalles Bibliográficos
Autores principales:	Nugraha, Alexander Patera, Kitaura, Hideki, Ohori, Fumitoshi, Pramusita, Adya, Ogawa, Saika, Noguchi, Takahiro, Marahleh, Aseel, Nara, Yasuhiko, Kinjo, Ria, Mizoguchi, Itaru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778739/ https://www.ncbi.nlm.nih.gov/pubmed/35014674 http://dx.doi.org/10.3892/mmr.2022.12594

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