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A Polylactide-Based Micellar Adjuvant Improves the Intensity and Quality of Immune Response

Micelles from amphiphilic polylactide-block-poly(N-acryloxysuccinimide-co-N-vinylpyrrolidone) (PLA-b-P(NAS-co-NVP)) block copolymers of 105 nm in size were characterized and evaluated in a vaccine context. The micelles were non-toxic in vitro (both in dendritic cells and HeLa cells). In vitro fluore...

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Detalles Bibliográficos
Autores principales: Lamrayah, Myriam, Phelip, Capucine, Coiffier, Céline, Lacroix, Céline, Willemin, Thibaut, Trimaille, Thomas, Verrier, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778782/
https://www.ncbi.nlm.nih.gov/pubmed/35057003
http://dx.doi.org/10.3390/pharmaceutics14010107