PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma

BACKGROUND: Immunotherapy, especially checkpoint inhibitors targeting PD-1 or PD-L1, has revolutionized cancer therapy. However, PD-1/PD-L1 inhibitors have not been investigated thoroughly in glioblastoma (GBM). Studies have shown that polymerase 1 and transcript release factor (PTRF/Cavin-1) has an...

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Detalles Bibliográficos
Autores principales: Yi, Kaikai, Cui, Xiaoteng, Liu, Xing, Wang, Yunfei, Zhao, Jixing, Yang, Shixue, Xu, Can, Yang, Eryan, Xiao, Menglin, Hong, Biao, Fang, Chuan, Kang, Chunsheng, Tan, Yanli, Wang, Qixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778801/
https://www.ncbi.nlm.nih.gov/pubmed/35069587
http://dx.doi.org/10.3389/fimmu.2021.802795

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