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Molecular Modeling Insights into Upadacitinib Selectivity upon Binding to JAK Protein Family

Rheumatoid arthritis (RA) is a chronic disease characterized by bone joint damage and incapacitation. The mechanism underlying RA pathogenesis is autoimmunity in the connective tissue. Cytokines play an important role in the human immune system for signal transduction and in the development of infla...

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Detalles Bibliográficos
Autores principales:	Taldaev, Amir, Rudnev, Vladimir R., Nikolsky, Kirill S., Kulikova, Liudmila I., Kaysheva, Anna L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778839/ https://www.ncbi.nlm.nih.gov/pubmed/35056087 http://dx.doi.org/10.3390/ph15010030

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