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Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease

Background: Polycystic kidney disease (PKD) is a genetic disorder affecting millions of people worldwide that is characterized by fluid-filled cysts and leads to end-stage renal disease (ESRD). The hallmarks of PKD are proliferation and dedifferentiation of tubular epithelial cells, cellular process...

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Detalles Bibliográficos
Autores principales: Djudjaj, Sonja, Kavvadas, Panagiotis, Prakoura, Niki, Bülow, Roman D., Migeon, Tiffany, Placier, Sandrine, Chadjichristos, Christos E., Boor, Peter, Chatziantoniou, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778905/
https://www.ncbi.nlm.nih.gov/pubmed/35055068
http://dx.doi.org/10.3390/ijms23020884