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Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease
Background: Polycystic kidney disease (PKD) is a genetic disorder affecting millions of people worldwide that is characterized by fluid-filled cysts and leads to end-stage renal disease (ESRD). The hallmarks of PKD are proliferation and dedifferentiation of tubular epithelial cells, cellular process...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778905/ https://www.ncbi.nlm.nih.gov/pubmed/35055068 http://dx.doi.org/10.3390/ijms23020884 |