Cargando…

CRISPR/CasRx Proof-of-Concept for RNA Degradation: A Future Tool against RNA Viruses?

Influenza viruses provide a great threat for the human population, causing highly contagious respiratory infections that can lead to serious clinical complications. There are a limited variety of influenza antivirals, and these antivirals are subjected to the constant emergence of resistances. There...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perez-SanJose, Diana, de la Fuente, Miguel Angel, Serna Pérez, Julia, Simarro, Maria, Eiros Bouza, José María, Sanz-Muñoz, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8778981/ https://www.ncbi.nlm.nih.gov/pubmed/35056089 http://dx.doi.org/10.3390/ph15010032

Ejemplares similares

Methods for in vitro CRISPR/CasRx-Mediated RNA Editing
por: Chuang, Yu-Fan, et al.
Publicado: (2021)

Programmable RNA Targeting Using CasRx in Flies
por: Buchman, Anna B., et al.
Publicado: (2020)

Engineered Extracellular Vesicle‐Delivered CRISPR/CasRx as a Novel RNA Editing Tool
por: Li, Tianwen, et al.
Publicado: (2023)

Preventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing
por: Zheng, Ziwen, et al.
Publicado: (2022)

CRISPR-CasRx Targeting LncRNA LINC00341 Inhibits Tumor Cell Growth in vitro and in vivo
por: Li, Chunjing, et al.
Publicado: (2021)

RNA targeting using CasRx can prevent aminoglycoside-induced hearing loss
por: Bofill-De Ros, Xavier
Publicado: (2022)

CRISPR/CasRx-Mediated RNA Knockdown Reveals That ACE2 Is Involved in the Regulation of Oligodendroglial Cell Morphological Differentiation
por: Kato, Yukino, et al.
Publicado: (2022)

Enhanced RNA knockdown efficiency with engineered fusion guide RNAs that function with both CRISPR-CasRx and hammerhead ribozyme
por: Zhan, Yonghao, et al.
Publicado: (2023)

Specific knockdown of Htra2 by CRISPR-CasRx prevents acquired sensorineural hearing loss in mice
por: Guo, Yang, et al.
Publicado: (2022)

Evaluating the Impact of gRNA SNPs in CasRx Activity for Reducing Viral RNA in HCoV-OC43
por: Mayes, Cathryn Michelle, et al.
Publicado: (2022)

Precise and efficient silencing of mutant Kras(G12D) by CRISPR-CasRx controls pancreatic cancer progression
por: Jiang, Wang, et al.
Publicado: (2020)

CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration
por: Zhou, Changyang, et al.
Publicado: (2020)

A Sensitive, Rapid, and Portable CasRx-based Diagnostic Assay for SARS-CoV-2
por: Brogan, Daniel J, et al.
Publicado: (2020)

Pan-Coronavirus CRISPR-CasRx Effector System Significantly Reduces Viable Titer in HCoV-OC43, HCoV-229E, and SARS-CoV-2
por: Mayes, Cathryn M., et al.
Publicado: (2023)

Homology-directed repair in mouse cells increased by CasRx-mediated knockdown or co-expressing Kaposi’s sarcoma-associated herpesvirus ORF52
por: Pan, Hong, et al.
Publicado: (2019)

Enhancement of protein translation by CRISPR/dCasRx coupled with SINEB2 repeat of noncoding RNAs
por: Cao, Congcong, et al.
Publicado: (2023)

RNA-dependent RNA targeting by CRISPR-Cas9
por: Strutt, Steven C, et al.
Publicado: (2018)

Ébola y virus emergentes
por: Eiros Bouza, José María, et al.
Publicado: (2015)

Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase
por: Xia, Zhen, et al.
Publicado: (2021)

Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system
por: Sokolowski, Richard D., et al.
Publicado: (2014)

Proof-of-concept for CRISPR/Cas9 gene editing in human preadipocytes: Deletion of FKBP5 and PPARG and effects on adipocyte differentiation and metabolism
por: Kamble, Prasad G., et al.
Publicado: (2020)

Commentary: RNA editing with CRISPR-Cas13
por: Matsoukas, Ianis G.
Publicado: (2018)

RNA-Targeting CRISPR–Cas Systems and Their Applications
por: Burmistrz, Michal, et al.
Publicado: (2020)

RNA-Dependent RNA Targeting by CRISPR-Cas Systems: Characterizations and Applications
por: Gunitseva, Natalia, et al.
Publicado: (2023)

CaSilico: A versatile CRISPR package for in silico CRISPR RNA designing for Cas12, Cas13, and Cas14
por: Asadbeigi, Adnan, et al.
Publicado: (2022)

Programmable RNA recognition and cleavage by CRISPR/Cas9
por: O’Connell, Mitchell R., et al.
Publicado: (2014)

Shooting the messenger: RNA-targetting CRISPR-Cas systems
por: Zhu, Yifan, et al.
Publicado: (2018)

Amplification-free RNA detection with CRISPR–Cas13
por: Shinoda, Hajime, et al.
Publicado: (2021)

Programmable RNA detection with CRISPR-Cas12a
por: Rananaware, Santosh R., et al.
Publicado: (2023)

Programmable RNA detection with CRISPR-Cas12a
por: Rananaware, Santosh R., et al.
Publicado: (2023)

Programmable RNA detection with CRISPR-Cas12a
por: Rananaware, Santosh R., et al.
Publicado: (2023)

Widespread CRISPR repeat-like RNA regulatory elements in CRISPR-Cas systems
por: Shmakov, Sergey A., et al.
Publicado: (2023)

Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs
por: Camara-Wilpert, Sarah, et al.
Publicado: (2023)

Vacunación frente al neumococo en adultos mayores de 65 años
por: López Gobernado, Miguel, et al.
Publicado: (2020)

CSC software corrects off-target mediated gRNA depletion in CRISPR-Cas9 essentiality screens
por: Perez, Alexendar R., et al.
Publicado: (2021)

RNA-guided gene activation by CRISPR-Cas9-based transcription factors
por: Perez-Pinera, Pablo, et al.
Publicado: (2013)

Heritable CRISPR-Cas9 editing of plant genomes using RNA virus vectors
por: Uranga, Mireia, et al.
Publicado: (2023)

The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems
por: Chylinski, Krzysztof, et al.
Publicado: (2013)

An AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept
por: Boender, Arjen J., et al.
Publicado: (2023)

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
por: Sternberg, Samuel H., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dn7659vcmj4g8cl1tefpqrth9j