Cargando…

Development of DNA Aptamers to Visualize Release of Mycobacterial Membrane-Derived Extracellular Vesicles in Infected Macrophages

Extracellular vesicles (EVs) have emerged into a novel vaccine platform, a biomarker and a nano-carrier for approved drugs. Their accurate detection and visualization are central to their utility in varied biomedical fields. Owing to the limitations of fluorescent dyes and antibodies, here, we descr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Das, Soonjyoti, Jain, Sapna, Ilyas, Mohd, Anand, Anjali, Kumar, Saurabh, Sharma, Nishant, Singh, Kuljit, Mahlawat, Rahul, Sharma, Tarun Kumar, Atmakuri, Krishnamohan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779091/ https://www.ncbi.nlm.nih.gov/pubmed/35056102 http://dx.doi.org/10.3390/ph15010045

Ejemplares similares

Comparative analysis of homologous aminopeptidase PepN from pathogenic and non-pathogenic mycobacteria reveals divergent traits
por: Sharma, Nishant, et al.
Publicado: (2019)

HupB, a nucleoid-associated protein, is critical for survival of Mycobacterium tuberculosis under host-mediated stresses and for enhanced tolerance to key first-line antibiotics
por: Singh, Niti, et al.
Publicado: (2022)

Rational truncation of aptamer for cross-species application to detect krait envenomation
por: Dhiman, Abhijeet, et al.
Publicado: (2018)

A novel G-quadruplex aptamer-based spike trimeric antigen test for the detection of SARS-CoV-2
por: Gupta, Ankit, et al.
Publicado: (2021)

Mycobacterial extracellular vesicles and host pathogen interactions
por: Gupta, Shamba, et al.
Publicado: (2018)

Aptamers in the Therapeutics and Diagnostics Pipelines
por: Kaur, Harleen, et al.
Publicado: (2018)

Aptamer-guided extracellular vesicle theranostics in oncology
por: Tran, Phuong H-L, et al.
Publicado: (2020)

Extracellular Vesicles in Mycobacterial Infections: Their Potential as Molecule Transfer Vectors
por: Wang, Jianjun, et al.
Publicado: (2019)

The extracellular matrix of mycobacterial biofilms: could we shorten the treatment of mycobacterial infections?
por: Chakraborty, Poushali, et al.
Publicado: (2019)

Biochemical and structural features of extracellular vesicle-binding RNA aptamers
por: Murakami, Kazuyoshi, et al.
Publicado: (2017)

Theranostic Application of a Novel G-Quadruplex-Forming DNA Aptamer Targeting Malate Synthase of Mycobacterium tuberculosis
por: Dhiman, Abhijeet, et al.
Publicado: (2019)

Identification and Engineering of Aptamers for Theranostic Application in Human Health and Disorders
por: Basu, Debleena, et al.
Publicado: (2021)

Comprehensive overview of extracellular vesicle proteomics in meningioma: future strategy
por: Rana, Rashmi, et al.
Publicado: (2021)

Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis
por: Gupta, Shamba, et al.
Publicado: (2023)

Rapid diagnosis of TB using Aptamer-based assays for Mycobacterium tuberculosis antigens in children and adolescents
por: Bethu, Rajesh, et al.
Publicado: (2023)

Diagnosis of genitourinary tuberculosis: detection of mycobacterial lipoarabinomannan and MPT-64 biomarkers within urine extracellular vesicles by nano-based immuno-PCR assay
por: Kamra, Ekta, et al.
Publicado: (2023)

Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles
por: Sun, Duanping, et al.
Publicado: (2023)

Aptamer-based diagnostic and therapeutic approaches in animals: Current potential and challenges
por: Devi, Sapna, et al.
Publicado: (2021)

Beyond Macromolecules: Extracellular Vesicles as Regulators of Inflammatory Diseases
por: Das, Kaushik, et al.
Publicado: (2023)

Extracellular vesicle-based biovectors in chronic wound healing: Biogenesis and delivery approaches
por: Garima, et al.
Publicado: (2023)

Anti-Mycobacterial Activity of Flavonoid and Pyrimidine Compounds
por: Garg, Saurabh, et al.
Publicado: (2022)

Role of extracellular vesicles secretion in paclitaxel resistance of prostate cancer cells
por: Kumar, Ashish, et al.
Publicado: (2022)

The multifaceted role of extracellular vesicles in prostate cancer-a review
por: Jain, Divya Prakash, et al.
Publicado: (2023)

Extracellular Vesicles in Triple–Negative Breast Cancer: Immune Regulation, Biomarkers, and Immunotherapeutic Potential
por: Das, Kaushik, et al.
Publicado: (2023)

G-Quadruplex-Forming DNA Aptamers Inhibit the DNA-Binding Function of HupB and Mycobacterium tuberculosis Entry into Host Cells
por: Kalra, Priya, et al.
Publicado: (2018)

Immunogenicity of Mycobacterial Extracellular Vesicles Isolated From Host-Related Conditions Informs About Tuberculosis Disease Status
por: Schirmer, Sebastian, et al.
Publicado: (2022)

Terminal Respiratory Oxidases: A Targetables Vulnerability of Mycobacterial Bioenergetics?
por: Bajeli, Sapna, et al.
Publicado: (2020)

Is the facial nerve at risk following surgical correction of mandibular condylar fracture: A systematic review and meta-analysis
por: Tandon, Sapna, et al.
Publicado: (2022)

An Accurate Method for the Qualitative Detection and Quantification of Mycobacterial Promoter Activity
por: Mishra, Saurabh, et al.
Publicado: (2013)

Mycobacterial tlyA gene product is localized to the cell-wall without signal sequence
por: Kumar, Santosh, et al.
Publicado: (2015)

Simple Methods and Rational Design for Enhancing Aptamer Sensitivity and Specificity
por: Kalra, Priya, et al.
Publicado: (2018)

Lipid vesicles chaperone an encapsulated RNA aptamer
por: Saha, Ranajay, et al.
Publicado: (2018)

Extracellular Vesicles Released from Mycobacterium tuberculosis-Infected Neutrophils Promote Macrophage Autophagy and Decrease Intracellular Mycobacterial Survival
por: Alvarez-Jiménez, Violeta D., et al.
Publicado: (2018)

Comparison of Antero-Posterior Lip Position in Most Favored Facial Profile of Jaipur Population
por: Sharma, Kuldeep, et al.
Publicado: (2022)

Extracellular Vesicles and Their Impact on the Biology of Protozoan Parasites
por: Sharma, Manu, et al.
Publicado: (2023)

microRNAs in Mycobacterial Infection: Modulation of Host Immune Response and Apoptotic Pathways
por: Agarwal, Riddhi Girdhar, et al.
Publicado: (2019)

Surface-Engineered Extracellular Vesicles in Cancer Immunotherapy
por: Johnson, Vinith, et al.
Publicado: (2023)

Role of Extracellular Vesicles in Cell Death and Inflammation
por: Sanwlani, Rahul, et al.
Publicado: (2021)

Redox-dependent condensation of the mycobacterial nucleoid by WhiB4
por: Chawla, Manbeena, et al.
Publicado: (2018)

A prospective study of non-tuberculous mycobacterial disease among tuberculosis suspects at a tertiary care centre in north India
por: Sharma, Surendra Kumar, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_74v1inp1mpee08g6ajscm0v66o