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Granzyme B PET Imaging in Response to In Situ Vaccine Therapy Combined with αPD1 in a Murine Colon Cancer Model

Immune checkpoint inhibitors (ICIs) block checkpoint receptors that tumours use for immune evasion, allowing immune cells to target and destroy cancer cells. Despite rapid advancements in immunotherapy, durable response rates to ICIs remains low. To address this, combination clinical trials are unde...

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Detalles Bibliográficos
Autores principales:	Hartimath, Siddesh V., Ramasamy, Boominathan, Xuan, Tan Yun, Rong, Tang Jun, Khanapur, Shivashankar, Cheng, Peter, Hwang, You Yi, Robins, Edward G., Goggi, Julian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779135/ https://www.ncbi.nlm.nih.gov/pubmed/35057046 http://dx.doi.org/10.3390/pharmaceutics14010150

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