Cargando…
An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer
Probiotics are living microbes that play a significant role in protecting the host in various ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is considered one of the most significant causes of death worldwide. Although cancer treatment has received much attention i...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779143/ https://www.ncbi.nlm.nih.gov/pubmed/35054452 http://dx.doi.org/10.3390/life12010059 |
_version_ | 1784637499156463616 |
---|---|
author | Sankarapandian, Vidya Venmathi Maran, Balu Alagar Rajendran, Ramya Lakshmi Jogalekar, Manasi P. Gurunagarajan, Sridharan Krishnamoorthy, Rajapandiyan Gangadaran, Prakash Ahn, Byeong-Cheol |
author_facet | Sankarapandian, Vidya Venmathi Maran, Balu Alagar Rajendran, Ramya Lakshmi Jogalekar, Manasi P. Gurunagarajan, Sridharan Krishnamoorthy, Rajapandiyan Gangadaran, Prakash Ahn, Byeong-Cheol |
author_sort | Sankarapandian, Vidya |
collection | PubMed |
description | Probiotics are living microbes that play a significant role in protecting the host in various ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is considered one of the most significant causes of death worldwide. Although cancer treatment has received much attention in recent years, the number of people suffering from neoplastic syndrome continues to increase. Despite notable improvements in the field of cancer therapy, tackling cancer has been challenging due to the multiple properties of cancer cells and their ability to evade the immune system. Probiotics alter the immunological and cellular responses by enhancing the epithelial barrier and stimulating the production of anti-inflammatory, antioxidant, and anticarcinogenic compounds, thereby reducing cancer burden and growth. The present review focuses on the various mechanisms underlying the role of probiotics in the prevention and treatment of cancer. |
format | Online Article Text |
id | pubmed-8779143 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87791432022-01-22 An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer Sankarapandian, Vidya Venmathi Maran, Balu Alagar Rajendran, Ramya Lakshmi Jogalekar, Manasi P. Gurunagarajan, Sridharan Krishnamoorthy, Rajapandiyan Gangadaran, Prakash Ahn, Byeong-Cheol Life (Basel) Review Probiotics are living microbes that play a significant role in protecting the host in various ways. Gut microbiota is one of the key players in maintaining homeostasis. Cancer is considered one of the most significant causes of death worldwide. Although cancer treatment has received much attention in recent years, the number of people suffering from neoplastic syndrome continues to increase. Despite notable improvements in the field of cancer therapy, tackling cancer has been challenging due to the multiple properties of cancer cells and their ability to evade the immune system. Probiotics alter the immunological and cellular responses by enhancing the epithelial barrier and stimulating the production of anti-inflammatory, antioxidant, and anticarcinogenic compounds, thereby reducing cancer burden and growth. The present review focuses on the various mechanisms underlying the role of probiotics in the prevention and treatment of cancer. MDPI 2022-01-02 /pmc/articles/PMC8779143/ /pubmed/35054452 http://dx.doi.org/10.3390/life12010059 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sankarapandian, Vidya Venmathi Maran, Balu Alagar Rajendran, Ramya Lakshmi Jogalekar, Manasi P. Gurunagarajan, Sridharan Krishnamoorthy, Rajapandiyan Gangadaran, Prakash Ahn, Byeong-Cheol An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
title | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
title_full | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
title_fullStr | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
title_full_unstemmed | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
title_short | An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer |
title_sort | update on the effectiveness of probiotics in the prevention and treatment of cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779143/ https://www.ncbi.nlm.nih.gov/pubmed/35054452 http://dx.doi.org/10.3390/life12010059 |
work_keys_str_mv | AT sankarapandianvidya anupdateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT venmathimaranbalualagar anupdateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT rajendranramyalakshmi anupdateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT jogalekarmanasip anupdateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT gurunagarajansridharan anupdateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT krishnamoorthyrajapandiyan anupdateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT gangadaranprakash anupdateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT ahnbyeongcheol anupdateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT sankarapandianvidya updateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT venmathimaranbalualagar updateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT rajendranramyalakshmi updateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT jogalekarmanasip updateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT gurunagarajansridharan updateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT krishnamoorthyrajapandiyan updateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT gangadaranprakash updateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer AT ahnbyeongcheol updateontheeffectivenessofprobioticsinthepreventionandtreatmentofcancer |