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Effects of 2-Methoxyestradiol, a Main Metabolite of Estradiol on Hepatic ABCA1 Expression in HepG2 Cells

ATP-binding cassette transporter A1 (ABCA1) is a key regulator of lipid efflux, and the absence of ABCA1 induces hepatic lipid accumulation, which is one of the major causes of fatty liver. 2-Methoxyestradiol (2-ME(2)) has been demonstrated to protect against fatty liver. In this study, we investiga...

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Detalles Bibliográficos
Autores principales:	Ibata, Tomohiro, Lyu, Jingya, Imachi, Hitomi, Fukunaga, Kensaku, Sato, Seisuke, Kobayashi, Toshihiro, Saheki, Takanobu, Yoshimura, Takafumi, Murao, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779252/ https://www.ncbi.nlm.nih.gov/pubmed/35057469 http://dx.doi.org/10.3390/nu14020288

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