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Alternative Extraction and Downstream Purification Processes for Anthocyanins

Anthocyanins are natural pigments displaying different attractive colors ranging from red, violet, to blue. These pigments present health benefits that increased their use in food, nutraceuticals, and the cosmetic industry. However, anthocyanins are mainly extracted through conventional methods that...

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Detalles Bibliográficos
Autores principales: Nunes, Ana N., Borges, Alexandra, Matias, Ana A., Bronze, Maria Rosário, Oliveira, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779312/
https://www.ncbi.nlm.nih.gov/pubmed/35056685
http://dx.doi.org/10.3390/molecules27020368
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author Nunes, Ana N.
Borges, Alexandra
Matias, Ana A.
Bronze, Maria Rosário
Oliveira, Joana
author_facet Nunes, Ana N.
Borges, Alexandra
Matias, Ana A.
Bronze, Maria Rosário
Oliveira, Joana
author_sort Nunes, Ana N.
collection PubMed
description Anthocyanins are natural pigments displaying different attractive colors ranging from red, violet, to blue. These pigments present health benefits that increased their use in food, nutraceuticals, and the cosmetic industry. However, anthocyanins are mainly extracted through conventional methods that are time-consuming and involve the use of organic solvents. Moreover, the chemical diversity of the obtained complex extracts make the downstream purification step challenging. Therefore, the growing demand of these high-value pigments has stimulated the interest in designing new, safe, cost-effective, and tunable strategies for their extraction and purification. The current review focuses on the potential application of compressed fluid-based (such as subcritical and supercritical fluid extraction and pressurized liquid extraction) and deep eutectic solvents-based extraction methods for the recovery of anthocyanins. In addition, an updated review of the application of counter-current chromatography for anthocyanins purification is provided as a faster and cost-effective alternative to preparative-scale HPLC.
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spelling pubmed-87793122022-01-22 Alternative Extraction and Downstream Purification Processes for Anthocyanins Nunes, Ana N. Borges, Alexandra Matias, Ana A. Bronze, Maria Rosário Oliveira, Joana Molecules Review Anthocyanins are natural pigments displaying different attractive colors ranging from red, violet, to blue. These pigments present health benefits that increased their use in food, nutraceuticals, and the cosmetic industry. However, anthocyanins are mainly extracted through conventional methods that are time-consuming and involve the use of organic solvents. Moreover, the chemical diversity of the obtained complex extracts make the downstream purification step challenging. Therefore, the growing demand of these high-value pigments has stimulated the interest in designing new, safe, cost-effective, and tunable strategies for their extraction and purification. The current review focuses on the potential application of compressed fluid-based (such as subcritical and supercritical fluid extraction and pressurized liquid extraction) and deep eutectic solvents-based extraction methods for the recovery of anthocyanins. In addition, an updated review of the application of counter-current chromatography for anthocyanins purification is provided as a faster and cost-effective alternative to preparative-scale HPLC. MDPI 2022-01-07 /pmc/articles/PMC8779312/ /pubmed/35056685 http://dx.doi.org/10.3390/molecules27020368 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nunes, Ana N.
Borges, Alexandra
Matias, Ana A.
Bronze, Maria Rosário
Oliveira, Joana
Alternative Extraction and Downstream Purification Processes for Anthocyanins
title Alternative Extraction and Downstream Purification Processes for Anthocyanins
title_full Alternative Extraction and Downstream Purification Processes for Anthocyanins
title_fullStr Alternative Extraction and Downstream Purification Processes for Anthocyanins
title_full_unstemmed Alternative Extraction and Downstream Purification Processes for Anthocyanins
title_short Alternative Extraction and Downstream Purification Processes for Anthocyanins
title_sort alternative extraction and downstream purification processes for anthocyanins
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779312/
https://www.ncbi.nlm.nih.gov/pubmed/35056685
http://dx.doi.org/10.3390/molecules27020368
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