Targeting Oxidative Phosphorylation-Proteasome Activity in Extracellular Detached Cells Promotes Anoikis and Inhibits Metastasis

Metastasis arises owing to tumor cells’ capacity to evade pro-apoptotic signals. Anoikis—the apoptosis of detached cells (from the extracellular matrix (ECM)) is often circumvented by metastatic cells as a result of biochemical and molecular transformations. These facilitate cells’ ability to surviv...

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Detalles Bibliográficos
Autores principales: Adeshakin, Funmilayo O., Adeshakin, Adeleye O., Liu, Zhao, Cheng, Jian, Zhang, Pengchao, Yan, Dehong, Zhang, Guizhong, Wan, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779336/
https://www.ncbi.nlm.nih.gov/pubmed/35054435
http://dx.doi.org/10.3390/life12010042

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