Nek2 Kinase Signaling in Malaria, Bone, Immune and Kidney Disorders to Metastatic Cancers and Drug Resistance: Progress on Nek2 Inhibitor Development

Cell cycle kinases represent an important component of the cell machinery that controls signal transduction involved in cell proliferation, growth, and differentiation. Nek2 is a mitotic Ser/Thr kinase that localizes predominantly to centrosomes and kinetochores and orchestrates centrosome disjuncti...

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Detalles Bibliográficos
Autores principales: Dana, Dibyendu, Das, Tuhin, Choi, Athena, Bhuiyan, Ashif I., Das, Tirtha K., Talele, Tanaji T., Pathak, Sanjai K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779408/
https://www.ncbi.nlm.nih.gov/pubmed/35056661
http://dx.doi.org/10.3390/molecules27020347

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