Detection of Low-Copy Human Virus DNA upon Prolonged Formalin Fixation

Formalin fixation, albeit an outstanding method for morphological and molecular preservation, induces DNA damage and cross-linking, which can hinder nucleic acid screening. This is of particular concern in the detection of low-abundance targets, such as persistent DNA viruses. In the present study,...

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Detalles Bibliográficos
Autores principales: Mielonen, Outi I., Pratas, Diogo, Hedman, Klaus, Sajantila, Antti, Perdomo, Maria F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779449/
https://www.ncbi.nlm.nih.gov/pubmed/35062338
http://dx.doi.org/10.3390/v14010133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779449/
https://www.ncbi.nlm.nih.gov/pubmed/35062338
http://dx.doi.org/10.3390/v14010133

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