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Solvent-Free Synthesis, In Vitro and In Silico Studies of Novel Potential 1,3,4-Thiadiazole-Based Molecules against Microbial Pathogens

A new series of 1,3,4-thiadiazoles was synthesized by the reaction of methyl 2-(4-hydroxy-3-methoxybenzylidene) hydrazine-1-carbodithioate (2) with selected derivatives of hydrazonoyl halide by grinding method at room temperature. The chemical structures of the newly synthesized derivatives were res...

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Detalles Bibliográficos
Autores principales: Shehadi, Ihsan A., Abdelrahman, Mohamad T., Abdelraof, Mohamed, Rashdan, Huda R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779762/
https://www.ncbi.nlm.nih.gov/pubmed/35056655
http://dx.doi.org/10.3390/molecules27020342