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Deletion of the Viral Thymidine Kinase in a Meq-Deleted Recombinant Marek’s Disease Virus Reduces Lymphoid Atrophy but Is Less Protective

Marek’s disease (MD) is a ubiquitous disease of domesticated chickens and its etiologic agent is the Gallid alphaherpesvirus 2 (GaHV-2), also known as Marek’s disease virus (MDV). MD is currently controlled by vaccination using live attenuated strains of MDV (e.g., CVI988/Rispens), non-pathogenic se...

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Detalles Bibliográficos
Autores principales: Conrad, Steven J., Oluwayinka, Eniope B., Heidari, Mohammad, Mays, Jody K., Dunn, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779792/
https://www.ncbi.nlm.nih.gov/pubmed/35056456
http://dx.doi.org/10.3390/microorganisms10010007